Reaction profile

The FDA adverse-event record for placental abnormality

12 FDA adverse-event reports reference placental abnormality (VeDDRA 784). See the species, breeds, and drugs most associated with it below.

12
reports citing this reaction
58.3%
death-coded share
Dog
most-affected species
Spinosad
most-associated drug
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12
Total Reports
7
Deaths
58.3%
Death Rate

Species Most Affected

Dog 6
Horse 4
Cattle 2

Breeds Most Affected

Dachshund - Miniature 2
Paint 2
Horse (other) 1
Spaniel - King Charles Cavalier 1
Brangus 1
Landseer (Continental-European type) 1
Rottweiler 1
Chihuahua 1
Quarter Horse 1
Holstein-Friesian also known as Holstein 1

Associated Drugs

Spinosad 3
Nitenpyram 3
Generic Nitenpyram 2
Ivermectin + Praziquantel 2
Diclofenac 1
Ivermectin 10 Mg/Ml Solution For Injection 1
Milbemycin Oxime + Spinosad 1
Pergolide Mesylate 1
Cloxacillin Benz Intramam Dc 1
Esherichia Coli Bacterin 1
Bvd Types 1&2, Pi3, Brsv And The 5 Most Common Strains Of Lepto 1

Placental abnormality Reaction Insights

12 reports name Placental abnormality; 7 recorded a death outcome (58.3% of reported events, not a population-level mortality rate). VeDDRA code: 784.

By species: Dog (6 reports), Horse (4 reports), Cattle (2 reports). By breed: Dachshund - Miniature (2), Paint (2), Horse (other) (1).

Most co-reported drugs: Spinosad (3 reports), Nitenpyram (3 reports), Generic Nitenpyram (2 reports), Ivermectin + Praziquantel (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.