Reaction profile

The FDA adverse-event record for placental abnormality

Name: Placental abnormality - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

12 FDA reports name placental abnormality, a lower-volume reaction in the CVM extract (VeDDRA 784). Plate stamps and neighbourhood peers follow.

#2395 of 2,481
by report volume (all reactions): 12
reports citing this reaction: 58.3%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Placental abnormality has 12 reports now versus 12 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Placental abnormality changes

FDA AER · VeDDRA plate

Code 784 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 12 reports
DEATH-HOT 58.3%
BOTTOM-DECILE #2395/2481
PHOTO-FINISH Agitated state of mind
SPECIES-DOG Dog · 6
DRUG-LEAD Spinosad · 3
DESK-WIDE 10 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Agitated state of mind (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Placental abnormality

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Placental abnormality

Placental abnormality: high death-coded share in the FDA AER plate

Signature read: 12 reports place Placental abnormality in the lower third of FDA AER volume (#2395 of 2,481). Report volume is lower-third scale: 12 named reports in the openFDA extract. Death-coded share is upper-third: 7 of 12 reports (58.3% of named reports). Nearest volume peer: Agitated state of mind (±0 reports). Lead species Dog (6). Lead co-reported drug Spinosad (3).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 6

Horse 4

Cattle 2

Breeds Most Affected

Dachshund - Miniature 2

Paint 2

Horse (other) 1

Spaniel - King Charles Cavalier 1

Landseer (Continental-European type) 1

Brangus 1

Rottweiler 1

Chihuahua 1

Quarter Horse 1

Holstein-Friesian also known as Holstein 1

Associated Drugs

Spinosad 3

Nitenpyram 3

Generic Nitenpyram 2

Ivermectin + Praziquantel 2

Diclofenac 1

Ivermectin 10 Mg/Ml Solution For Injection 1

Milbemycin Oxime + Spinosad 1

Pergolide Mesylate 1

Cloxacillin Benz Intramam Dc 1

Esherichia Coli Bacterin 1

Bvd Types 1&2, Pi3, Brsv And The 5 Most Common Strains Of Lepto 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Placental abnormality (#2395 of 2,481 by report volume); death-coded 58.3%. PlainBreed reaction plate · report volume stamp 12 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →