Reaction profile

The FDA adverse-event record for weak pulse

580 FDA adverse-event reports reference weak pulse (VeDDRA 2187). See the species, breeds, and drugs most associated with it below.

580
reports citing this reaction
40.5%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
580
Total Reports
235
Deaths
40.5%
Death Rate

Species Most Affected

Dog 508
Cat 63
Horse 7
Alpaca 1
Cattle 1

Breeds Most Affected

Retriever - Labrador 58
Crossbred Canine/dog 40
Domestic Shorthair 39
Terrier - Bull - American Pit 24
Terrier - Yorkshire 24
Shih Tzu 23
Retriever - Golden 22
Boxer (German Boxer) 21
Shepherd Dog - German 19
Chihuahua 16

Associated Drugs

Moxidectin 171
Maropitant Citrate 79
Gabapentin 43
Carprofen 39
Milbemycin Oxime + Spinosad 27
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 27
Rabies Virus, Kv 26
Melarsomine Dihydrochloride 24
Rabies Virus, 24
Bedinvetmab 24
Diphenhydramine 23
Diphenhydramine Hcl 22
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 22
Isoflurane 22
Epinephrine 21
Famotidine 21
Dexamethasone Sodium Phosphate 20
Deracoxib 20
Dexmedetomidine Hydrochloride 19
Buprenorphine 18

Weak pulse Reaction Insights

580 reports name Weak pulse; 235 recorded a death outcome (40.5% of reported events, not a population-level mortality rate). VeDDRA code: 2187.

By species: Dog (508 reports), Cat (63 reports), Horse (7 reports). By breed: Retriever - Labrador (58), Crossbred Canine/dog (40), Domestic Shorthair (39).

Most co-reported drugs: Moxidectin (171 reports), Maropitant Citrate (79 reports), Gabapentin (43 reports), Carprofen (39 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.