Reaction profile

The FDA adverse-event record for weak pulse

635 FDA reports name weak pulse, a high-volume reaction in the CVM extract (VeDDRA 2187). Plate stamps and neighbourhood peers follow.

#554 of 2,481
by report volume (all reactions)
635
reports citing this reaction
41.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Weak pulse has 635 reports now versus 605 in that prior snapshot: 30 more (5.0%).

Report change
+30
Death-coded reports
+13
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Weak pulse changes

FDA AER · VeDDRA plate

Code 2187 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 635 reports
  • DEATH-HOT 41.1%
  • UPPER-Q #554/2481
  • PHOTO-FINISH Circulatory collapse…
  • SPECIES-DOG Dog · 547
  • DRUG-LEAD Moxidectin · 183
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Circulatory collapse (see also 'Neurological' and 'Systemic disorders') (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Weak pulse

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Partial anorexia · near638Hair coat discolourat… · near637Circulatory collapse… · near636Weak pulse · this reaction635Abdominal mass · near633Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Weak pulse

Weak pulse: high death-coded share in the FDA AER plate

Signature read: 261 death-coded reports is a heavy tail count for Weak pulse in the CVM extract. Report volume is upper-third scale: 635 named reports in the openFDA extract. Death-coded share is upper-third: 261 of 635 reports (41.1% of named reports). Nearest volume peer: Circulatory collapse (see also 'Neurological' and 'Systemic disorders') (±1 reports). Lead species Dog (547). Lead co-reported drug Moxidectin (183).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 547
Cat 79
Horse 7
Alpaca 1
Cattle 1

Breeds Most Affected

Retriever - Labrador 63
Domestic Shorthair 51
Crossbred Canine/dog 43
Terrier - Bull - American Pit 26
Terrier - Yorkshire 25
Shih Tzu 25
Retriever - Golden 23
Boxer (German Boxer) 22
Shepherd Dog - German 19
Chihuahua 16

Associated Drugs

Moxidectin 183
Maropitant Citrate 90
Gabapentin 50
Carprofen 39
Rabies Virus, Kv 30
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 30
Milbemycin Oxime + Spinosad 28
Isoflurane 27
Bedinvetmab 26
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 25
Diphenhydramine 25
Melarsomine Dihydrochloride 25
Buprenorphine 24
Rabies Virus, 24
Epinephrine 22
Diphenhydramine Hcl 22
Famotidine 21
Prednisone 20
Dexamethasone Sodium Phosphate 20
Deracoxib 20

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Weak pulse, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (41.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Weak pulse (#554 of 2,481 by report volume); death-coded 41.1%. PlainBreed reaction plate · death-coded report count stamp 261 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →