Weak pulse

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VeDDRA Code: 2187

580 adverse event reports referencing this reaction

580
Total Reports
235
Deaths
4050.0%
Death Rate

Species Most Affected

Dog 508
Cat 63
Horse 7
Alpaca 1
Cattle 1

Breeds Most Affected

Retriever - Labrador 58
Crossbred Canine/dog 40
Domestic Shorthair 39
Terrier - Bull - American Pit 24
Terrier - Yorkshire 24
Shih Tzu 23
Retriever - Golden 22
Boxer (German Boxer) 21
Shepherd Dog - German 19
Chihuahua 16

Associated Drugs

Moxidectin 171
Maropitant Citrate 79
Gabapentin 43
Carprofen 39
Milbemycin Oxime + Spinosad 27
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 27
Rabies Virus, Kv 26
Melarsomine Dihydrochloride 24
Rabies Virus, 24
Bedinvetmab 24
Diphenhydramine 23
Diphenhydramine Hcl 22
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 22
Isoflurane 22
Epinephrine 21
Famotidine 21
Dexamethasone Sodium Phosphate 20
Deracoxib 20
Dexmedetomidine Hydrochloride 19
Buprenorphine 18

Data Summary

Metric Value
Total reports referencing reaction 580
Reports with fatal outcome 235
Case-fatality rate (reported events) 4050.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2187.

Weak pulse Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 580 adverse event reports that reference Weak pulse as a reaction term, including 235 reports with a death outcome — a 4050.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2187, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Weak pulse appears most frequently in reports for Dog (508 reports), Cat (63 reports), Horse (7 reports) — with Dog dominating at 508 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (58), Crossbred Canine/dog (40), Domestic Shorthair (39). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Weak pulse are Moxidectin (171 reports), Maropitant Citrate (79 reports), Gabapentin (43 reports), Carprofen (39 reports), with Moxidectin appearing alongside this reaction in 171 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial