Reaction profile

The FDA adverse-event record for clenched jaw

Name: Clenched jaw - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

38 FDA reports name clenched jaw, a lower-volume reaction in the CVM extract (VeDDRA 3101). Plate stamps and neighbourhood peers follow.

#1868 of 2,481
by report volume (all reactions): 38
reports citing this reaction: 13.2%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Clenched jaw has 38 reports now versus 32 in that prior snapshot: 6 more (18.8%).

Report change: +6
Death-coded reports: +0
Death-coded share: −2.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Clenched jaw changes

FDA AER · VeDDRA plate

Code 3101 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 38 reports
DEATH-ELEV 13.2%
LOWER-Q #1868/2481
PHOTO-FINISH Conjunctival reddening
SPECIES-DOG Dog · 34
DRUG-LEAD Pyrantel Pamoate;… · 6
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Conjunctival reddening (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Clenched jaw

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Clenched jaw

What the FDA AER plate says about Clenched jaw

Signature read: 38 reports place Clenched jaw in the lower third of FDA AER volume (#1868 of 2,481). Report volume is lower-third scale: 38 named reports in the openFDA extract. 5 of 38 reports were death-coded (13.2% of named reports, not a population mortality rate). Nearest volume peer: Conjunctival reddening (±0 reports). Lead species Dog (34). Lead co-reported drug Pyrantel Pamoate;Sarolaner (6).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Pyrantel Pamoate;Sarolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 34

Cat 3

Pig 1

Breeds Most Affected

Dog (unknown) 3

Hound (unspecified) 2

Crossbred Canine/dog 2

Chihuahua 2

Retriever - Labrador 2

Domestic Shorthair 2

Shepherd Dog - Australian 2

Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2

Poodle - Toy 1

Terrier - Rat 1

Associated Drugs

Pyrantel Pamoate;Sarolaner 6

Bedinvetmab 5

Carprofen 4

Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet 4

Mirtazapine 3

Ivermectin + Pyrantel As Pamoate Salt 2

Oclacitinib Maleate 2

Ursodiol 2

Tramadol 2

Entyce 2

Milbemycin Oxime + Praziquantel 2

Maropitant Citrate 2

Subcutaneous Fluids 2

Afoxolaner 9.375Mg / Moxidectin 45Mcg / Pyrantel 18.75Mg Chewable Tablet 2

Diphenhydramine 2

Eprinomectin + Esafoxolaner + Praziquantel 2

Propofol 2

Isoflurane 2

Afoxolaner 2

Milbemycin Oxime + Spinosad 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Clenched jaw (#1868 of 2,481 by report volume); death-coded 13.2%. PlainBreed reaction plate · report volume stamp 38 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →