Reaction profile

The FDA adverse-event record for nt - hepatic lipidosis (steatosis)

31 FDA reports name nt - hepatic lipidosis (steatosis), a lower-volume reaction in the CVM extract (VeDDRA 2321). Plate stamps and neighbourhood peers follow.

#1978 of 2,481
by report volume (all reactions)
31
reports citing this reaction
90.3%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. NT - hepatic lipidosis (steatosis) has 31 reports now versus 31 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to NT - hepatic lipidosis (steatosis) changes

FDA AER · VeDDRA plate

Code 2321 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 31 reports
  • DEATH-HOT 90.3%
  • LOWER-Q #1978/2481
  • PHOTO-FINISH ABNORMAL TEST RESULT,…
  • SPECIES-CAT Cat · 15
  • DRUG-LEAD Fluralaner Chew T… · 6
  • DESK-WIDE 19 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around NT - hepatic lipidosis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ABNORMAL TEST RESULT,… · near31ALBUMIN HIGH, URINE · near31BILE ACIDS ABNORMAL,… · near31Clonic seizure · near31NT - hepatic lipidosi… · thi…31Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around NT - hepatic lipidosis (steatosis)

NT - hepatic lipidosis (steatosis): high death-coded share in the FDA AER plate

Signature read: NT - hepatic lipidosis (steatosis)'s 90.3% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 31 named reports in the openFDA extract. Death-coded share is upper-third: 28 of 31 reports (90.3% of named reports). Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports). Lead species Cat (15). Lead co-reported drug Fluralaner Chew Tablets (6).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 15
Dog 13
Sheep 1
Cattle 1
Horse 1

Breeds Most Affected

Domestic Shorthair 10
Crossbred Canine/dog 4
Sheep (unknown) 1
Sheepdog - Shetland 1
Chihuahua 1
Crossbred Feline/cat 1
Spaniel - King Charles Cavalier 1
Spitz - German Pomeranian 1
Persian 1
Dog (other) 1

Associated Drugs

Fluralaner Chew Tablets 6
Afoxolaner 3
Fluralaner Spot-On Solution 3
Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride 3
Ivermectin + Pyrantel As Pamoate Salt 2
Cefovecin 2
Maropitant Citrate 2
Selamectin;Sarolaner 2
Oxfendazole 1
Dexmedetomidine Hydrochloride 1
Ketamine Hydrochloride 1
Butorphanol Tartrate 1
Marbofloxacin 1
Cyproheptadine Hcl 1
Hydromorphone Hcl 1
Oclacitinib Maleate 1
Cyclosporine A 1
Midazolam Hydrochloride 1
Fenbendazole 1
Nitenpyram 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for NT - hepatic lipidosis (steatosis) (#1978 of 2,481 by report volume); death-coded 90.3%. PlainBreed reaction plate · death-coded share stamp 90.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →