Reaction profile

The FDA adverse-event record for off food

56 FDA adverse-event reports reference off food (VeDDRA 2740). See the species, breeds, and drugs most associated with it below.

56
reports citing this reaction
25.0%
death-coded share
Dog
most-affected species
Monensin Sodium
most-associated drug
Verify with FDA CVM →
56
Total Reports
14
Deaths
25.0%
Death Rate

Species Most Affected

Dog 19
Horse 12
Cattle 7
Cat 7
Pig 3
Turkey 3
Chicken 3
Chinchilla 1
Goat 1

Breeds Most Affected

Quarter Horse 9
Retriever - Labrador 5
Cattle (other) 3
Turkey (unknown) 3
Dog (unknown) 3
Domestic Shorthair 3
Commercial hybrid 2
Unknown 2
Pit Bull 2
Domestic Mediumhair 2

Associated Drugs

Monensin Sodium 6
Trilostane 5
Clodronate Disodium 4
Narasin 3
Levothyroxine 3
Pyrantel Pamoate;Sarolaner 3
Hyaluronic Acid 3
6 Way Vaccine 3
Carbocaine 2% 3
Amikacin 3
Fenbendazol Oral Paste 2
Prednisone 2
Flunixin Meglumine 2
Fluralaner Spot-On Solution 2
Ceftiofur Crystalline Free Acid 2
Tigilanol Tiglate 2
Ketamine 2
Diphenhydramine 2
Bexagliflozin 2
Bedinvetmab 2

Off food Reaction Insights

56 reports name Off food; 14 recorded a death outcome (25.0% of reported events, not a population-level mortality rate). VeDDRA code: 2740.

By species: Dog (19 reports), Horse (12 reports), Cattle (7 reports). By breed: Quarter Horse (9), Retriever - Labrador (5), Cattle (other) (3).

Most co-reported drugs: Monensin Sodium (6 reports), Trilostane (5 reports), Clodronate Disodium (4 reports), Narasin (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.