Reaction profile

The FDA adverse-event record for abnormal test result

377 FDA adverse-event reports reference abnormal test result (VeDDRA 1221). See the species, breeds, and drugs most associated with it below.

377
reports citing this reaction
33.7%
death-coded share
Dog
most-affected species
Ivermectin + Pyrantel As Pamoate Salt
most-associated drug
Verify with FDA CVM →
377
Total Reports
127
Deaths
33.7%
Death Rate

Species Most Affected

Dog 235
Cattle 124
Cat 14
Pig 2
Sheep 1
Horse 1

Breeds Most Affected

Cattle (other) 64
Retriever - Labrador 35
Mixed (Cattle) 35
Retriever - Golden 18
Shepherd Dog - German 14
Beagle 14
Holstein-Friesian also known as Holstein 11
Crossbred Canine/dog 11
Shih Tzu 9
Domestic Shorthair 8

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 127
Ceftiofur Crystalline Free Acid 71
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 51
Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 48
Tulathromycin 42
Bovine Viral Diarrhea Virus, Type 2, Strain 53637, Lot Bvd2Mlv-D; Bovine Viral D 26
Milbemycin Oxime, Lufenuron 22
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 21
Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost 18
Doramectin; Phenol 15
Doramectin 10
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Infectious Bovine Rhin 10
Milbemcyin Oxime, Lufenuron, Praziquantel 10
Albendazole 9
Recombinant Human Insulin 9
Maropitant Citrate 7
Metronidazole 7
Fluralaner Chew Tablets 7
Imidacloprid + Moxidectin 6
Oclacitinib Maleate 6

Abnormal test result Reaction Insights

377 reports name Abnormal test result; 127 recorded a death outcome (33.7% of reported events, not a population-level mortality rate). VeDDRA code: 1221.

By species: Dog (235 reports), Cattle (124 reports), Cat (14 reports). By breed: Cattle (other) (64), Retriever - Labrador (35), Mixed (Cattle) (35).

Most co-reported drugs: Ivermectin + Pyrantel As Pamoate Salt (127 reports), Ceftiofur Crystalline Free Acid (71 reports), Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn (51 reports), Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia (48 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.