Reaction profile

The FDA adverse-event record for lack of efficacy (endoparasite) - lungworm

Name: Lack of efficacy (endoparasite) - lungworm - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

14 FDA reports name lack of efficacy (endoparasite) - lungworm, a lower-volume reaction in the CVM extract (VeDDRA 3002). Plate stamps and neighbourhood peers follow.

#2329 of 2,481
by report volume (all reactions): 14
reports citing this reaction: 0.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (endoparasite) - lungworm has 14 reports now versus 13 in that prior snapshot: 1 more (7.7%).

Report change: +1
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (endoparasite) - lungworm changes

FDA AER · VeDDRA plate

Code 3002 VOL-TRACE

VOL-TRACE · DEATH-RARE · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 14 reports
DEATH-RARE 0.0%
BOTTOM-DECILE #2329/2481
PHOTO-FINISH Addisonian crisis
SPECIES-DOG Dog · 12
DRUG-LEAD Pyrantel Pamoate;… · 4
DESK-WIDE 10 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Addisonian crisis (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of efficacy - lungworm

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Lack of efficacy (endoparasite) - lungworm

Lack of efficacy (endoparasite) - lungworm: low death-coded share in the FDA AER plate

Signature read: 14 reports place Lack of efficacy (endoparasite) - lungworm in the lower third of FDA AER volume (#2329 of 2,481). Report volume is lower-third scale: 14 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 14 reports (0.0% of named reports). Nearest volume peer: Addisonian crisis (±0 reports). Lead species Dog (12). Lead co-reported drug Pyrantel Pamoate;Sarolaner (4).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Pyrantel Pamoate;Sarolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 12

Cat 2

Breeds Most Affected

Shepherd Dog - German 3

Retriever - Labrador 2

Domestic Shorthair 2

Setter - English 1

Retriever - Golden 1

Dog (unknown) 1

Boxer (German Boxer) 1

Schnauzer - Miniature 1

Pointer (unspecified) 1

Crossbred Canine/dog 1

Associated Drugs

Pyrantel Pamoate;Sarolaner 4

Moxidectin 3

Fenbendazole 2

Ivermectin + Pyrantel As Pamoate Salt 2

Afoxolaner 2

Milbemycin Oxime + Praziquantel 1

Dewormer (Unknown) 1

Eprinomectin + Esafoxolaner + Praziquantel 1

Imidacloprid + Moxidectin 1

Prednisolone 1

Amoxicillin Trihydrate + Clavulanate Potassium 1

Milbemycin Oxime,Praziquantel Micronized 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (endoparasite) - lungworm (#2329 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · report volume stamp 14 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →