Reaction profile

The FDA adverse-event record for liver tumour

311 FDA adverse-event reports reference liver tumour (VeDDRA 505). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#850 of 2,481
by report volume (all reactions)
311
reports citing this reaction
51.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Liver tumour has 311 reports now versus 305 in that prior snapshot: 6 more (2.0%).

Report change
+6
Death-coded reports
+4
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Liver tumour changes

FDA AER · VeDDRA plate

Code 505 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 311 reports
  • DEATH-HOT 51.4%
  • MID-PACK #850/2481
  • PHOTO-FINISH Elevated haematocrit
  • SPECIES-DOG Dog · 291
  • DRUG-LEAD Trilostane · 68
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Elevated haematocrit (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Liver tumour

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Addison's disease · near312Elevated haematocrit · near311Liver tumour · this reaction311Swollen feet · near311Unconscious · near311Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Liver tumour

Liver tumour: high death-coded share in the FDA AER plate

Signature read: Liver tumour's 51.4% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 160 of 311 reports (51.4% of named reports). Nearest volume peer: Elevated haematocrit (±0 reports). Lead species Dog (291). Lead co-reported drug Trilostane (68).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 291
Cat 20

Breeds Most Affected

Retriever - Labrador 39
Crossbred Canine/dog 27
Retriever - Golden 26
Domestic Shorthair 14
Shepherd Dog - German 14
Dog (unknown) 12
Shih Tzu 10
Chihuahua 8
Siberian Husky 7
Terrier - Jack Russell 7

Associated Drugs

Trilostane 68
Oclacitinib Maleate 50
Carprofen 33
Bedinvetmab 27
Milbemycin Oxime + Spinosad 25
Maropitant Citrate 23
Ivermectin + Pyrantel As Pamoate Salt 17
Gabapentin 15
Metronidazole 13
Fluralaner Chew Tablets 13
Moxidectin 12
Prednisone 11
Afoxolaner 9
Spinosad 8
Enrofloxacin 8
Polysulfated Glycosaminoglycan 8
Grapiprant 8
Fluralaner 13.64% 12-Week Chew 7
Deracoxib 6
Milbemycin Oxime + Praziquantel 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Liver tumour, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (311 here).

Similar death-coded share

Nearest other reactions by death-coded share (51.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Liver tumour (#850 of 2,481 by report volume); death-coded 51.4%. PlainBreed reaction plate · death-coded share stamp 51.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →