Reaction profile

The FDA adverse-event record for liver tumour

299 FDA adverse-event reports reference liver tumour (VeDDRA 505). See the species, breeds, and drugs most associated with it below.

299
reports citing this reaction
50.8%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
299
Total Reports
152
Deaths
50.8%
Death Rate

Species Most Affected

Dog 280
Cat 19

Breeds Most Affected

Retriever - Labrador 37
Crossbred Canine/dog 26
Retriever - Golden 25
Shepherd Dog - German 14
Domestic Shorthair 13
Dog (unknown) 12
Shih Tzu 9
Chihuahua 8
Siberian Husky 7
Terrier - Jack Russell 7

Associated Drugs

Trilostane 64
Oclacitinib Maleate 50
Carprofen 31
Milbemycin Oxime + Spinosad 25
Bedinvetmab 24
Maropitant Citrate 23
Ivermectin + Pyrantel As Pamoate Salt 17
Metronidazole 13
Gabapentin 13
Fluralaner Chew Tablets 13
Moxidectin 12
Prednisone 11
Afoxolaner 9
Spinosad 8
Enrofloxacin 8
Polysulfated Glycosaminoglycan 8
Grapiprant 8
Fluralaner 13.64% 12-Week Chew 7
Deracoxib 6
Milbemycin Oxime + Praziquantel 6

Liver tumour Reaction Insights

299 reports name Liver tumour; 152 recorded a death outcome (50.8% of reported events, not a population-level mortality rate). VeDDRA code: 505.

By species: Dog (280 reports), Cat (19 reports). By breed: Retriever - Labrador (37), Crossbred Canine/dog (26), Retriever - Golden (25).

Most co-reported drugs: Trilostane (64 reports), Oclacitinib Maleate (50 reports), Carprofen (31 reports), Milbemycin Oxime + Spinosad (25 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.