Reaction profile

The FDA adverse-event record for founder

Name: Founder - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

22 FDA reports name founder, a lower-volume reaction in the CVM extract (VeDDRA 616). Plate stamps and neighbourhood peers follow.

#2125 of 2,481
by report volume (all reactions): 22
reports citing this reaction: 27.3%
death-coded share: Horse
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Founder has 22 reports now versus 20 in that prior snapshot: 2 more (10.0%).

Report change: +2
Death-coded reports: +0
Death-coded share: −2.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Founder changes

FDA AER · VeDDRA plate

Code 616 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-HORSE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 22 reports
DEATH-HOT 27.3%
LOWER-Q #2125/2481
PHOTO-FINISH Adenocarcinoma NOS
SPECIES-HORSE Horse · 17
DRUG-LEAD Pergolide Mesylate · 7
DESK-WIDE 13 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Adenocarcinoma NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Founder

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Founder

Founder: high death-coded share in the FDA AER plate

Signature read: 22 reports place Founder in the lower third of FDA AER volume (#2125 of 2,481). Report volume is lower-third scale: 22 named reports in the openFDA extract. Death-coded share is upper-third: 6 of 22 reports (27.3% of named reports). Nearest volume peer: Adenocarcinoma NOS (±0 reports). Lead species Horse (17). Lead co-reported drug Pergolide Mesylate (7).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Horse 17

Cattle 4

Donkey 1

Breeds Most Affected

Horse (unknown) 4

Quarter Horse 4

Thoroughbred 3

Aberdeen Angus 2

Donkey (unknown) 1

Cattle (unknown) 1

Mixed (Cattle) 1

Trakehner 1

Palomino 1

Horse (other) 1

Associated Drugs

Pergolide Mesylate 7

Monensin Sodium 4

Polysulfated Glycosaminoglycan 2

Tylosin Tartrate 2

Firocoxib 0.82% 1

Ractopamine Hydrochloride 1

Triamcinolone Acetonide 1

Ewt Vaccine 1

West Nile Vaccine 1

Flu/Rhino Vaccine 1

Hyaluronic Acid Injection 1

Bute Paste 1

Amikacin 1

Detomidine Hydrochloride 1

Lasalocid Sodium 1

Pergolide 1

Fenbendazol Oral Paste 1

Hcg (Fd) Injectable 1

Joint Supplement (Unspecified) 1

Rabies Virus,Pv-11,Killed 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Founder (#2125 of 2,481 by report volume); death-coded 27.3%. PlainBreed reaction plate · report volume stamp 22 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →