Reaction profile

The FDA adverse-event record for founder

19 FDA adverse-event reports reference founder (VeDDRA 616). See the species, breeds, and drugs most associated with it below.

19
reports citing this reaction
31.6%
death-coded share
Horse
most-affected species
Pergolide Mesylate
most-associated drug
Verify with FDA CVM →
19
Total Reports
6
Deaths
31.6%
Death Rate

Species Most Affected

Horse 16
Cattle 2
Donkey 1

Breeds Most Affected

Horse (unknown) 4
Thoroughbred 3
Quarter Horse 3
Donkey (unknown) 1
Cattle (unknown) 1
Trakehner 1
Mixed (Cattle) 1
Palomino 1
Horse (other) 1
Haflinger 1

Associated Drugs

Pergolide Mesylate 7
Monensin Sodium 4
Polysulfated Glycosaminoglycan 2
Firocoxib 0.82% 1
Ractopamine Hydrochloride 1
Triamcinolone Acetonide 1
Ewt Vaccine 1
West Nile Vaccine 1
Flu/Rhino Vaccine 1
Hyaluronic Acid Injection 1
Bute Paste 1
Amikacin 1
Detomidine Hydrochloride 1
Lasalocid Sodium 1
Pergolide 1
Hcg (Fd) Injectable 1
Fenbendazol Oral Paste 1
Joint Supplement (Unspecified) 1
Rabies Virus,Pv-11,Killed 1
Unknown Sedation 1

Founder Reaction Insights

19 reports name Founder; 6 recorded a death outcome (31.6% of reported events, not a population-level mortality rate). VeDDRA code: 616.

By species: Horse (16 reports), Cattle (2 reports), Donkey (1 reports). By breed: Horse (unknown) (4), Thoroughbred (3), Quarter Horse (3).

Most co-reported drugs: Pergolide Mesylate (7 reports), Monensin Sodium (4 reports), Polysulfated Glycosaminoglycan (2 reports), Firocoxib 0.82% (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.