Reaction profile

The FDA adverse-event record for anal prolapse

12 FDA reports name anal prolapse, a lower-volume reaction in the CVM extract (VeDDRA 256). Plate stamps and neighbourhood peers follow.

#2376 of 2,481
by report volume (all reactions)
12
reports citing this reaction
25.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Anal prolapse has 12 reports now versus 11 in that prior snapshot: 1 more (9.1%).

Report change
+1
Death-coded reports
+0
Death-coded share
−2.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Anal prolapse changes

FDA AER · VeDDRA plate

Code 256 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 12 reports
  • DEATH-HOT 25.0%
  • BOTTOM-DECILE #2376/2481
  • PHOTO-FINISH Agitated state of mind
  • SPECIES-DOG Dog · 5
  • DRUG-LEAD Praziquantel · 2
  • DESK-WIDE 10 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Agitated state of mind (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Anal prolapse

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Agitated state of mind · near12Airsacculitis · near12Anal prolapse · this reaction12Anal sac adenocarcioma · near12BILIRUBIN(INDIRECT) H… · near12Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Anal prolapse

Anal prolapse: high death-coded share in the FDA AER plate

Signature read: 12 reports place Anal prolapse in the lower third of FDA AER volume (#2376 of 2,481). Report volume is lower-third scale: 12 named reports in the openFDA extract. Death-coded share is upper-third: 3 of 12 reports (25.0% of named reports). Nearest volume peer: Agitated state of mind (±0 reports). Lead species Dog (5). Lead co-reported drug Praziquantel (2).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 5
Cat 4
Pig 2
Fish 1

Breeds Most Affected

Crossbred Canine/dog 2
Domestic Shorthair 2
Bulldog 1
Duroc 1
Pig (unknown) 1
Maltese 1
Fish (other) 1
Cat (unknown) 1
Himalayan 1
Spitz - German Pomeranian 1

Associated Drugs

Praziquantel 2
Maropitant Citrate 2
Imidacloprid + Moxidectin 1
Enrofloxacin 1
Swine Influenza Vaccine 1
Narasin 1
Beta-Glucanase + Beta-Mannanase 1
Prednisolone; Trimeprazine Tartrate 1
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 1
Bordetella Bronchiseptica, Strain 78-9159, Kb 1
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 1
Rabies Virus, Kv 1
Ivermectin + Pyrantel As Pamoate Salt 1
Florfenicol Inj Sol 30% W Pg 1
Genta/Momet/Clotrim Ear Oint 1
Praziquantel + Pyrantel 1
Fluralaner 13.64% 12-Week Chew 1
Capromorelin 1
Canine Parvovirus Mab 1
Metronidazole 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Anal prolapse (#2376 of 2,481 by report volume); death-coded 25.0%. PlainBreed reaction plate · report volume stamp 12 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →