Reaction profile

The FDA adverse-event record for anal prolapse

11 FDA adverse-event reports reference anal prolapse (VeDDRA 256). See the species, breeds, and drugs most associated with it below.

11
reports citing this reaction
27.3%
death-coded share
Dog
most-affected species
Praziquantel
most-associated drug
Verify with FDA CVM →
11
Total Reports
3
Deaths
27.3%
Death Rate

Species Most Affected

Dog 4
Cat 4
Pig 2
Fish 1

Breeds Most Affected

Crossbred Canine/dog 2
Domestic Shorthair 2
Bulldog 1
Duroc 1
Pig (unknown) 1
Maltese 1
Fish (other) 1
Cat (unknown) 1
Himalayan 1

Associated Drugs

Praziquantel 2
Imidacloprid + Moxidectin 1
Enrofloxacin 1
Swine Influenza Vaccine 1
Narasin 1
Beta-Glucanase + Beta-Mannanase 1
Prednisolone; Trimeprazine Tartrate 1
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 1
Bordetella Bronchiseptica, Strain 78-9159, Kb 1
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 1
Rabies Virus, Kv 1
Ivermectin + Pyrantel As Pamoate Salt 1
Florfenicol Inj Sol 30% W Pg 1
Genta/Momet/Clotrim Ear Oint 1
Praziquantel + Pyrantel 1
Fluralaner 13.64% 12-Week Chew 1

Anal prolapse Reaction Insights

11 reports name Anal prolapse; 3 recorded a death outcome (27.3% of reported events, not a population-level mortality rate). VeDDRA code: 256.

By species: Dog (4 reports), Cat (4 reports), Pig (2 reports). By breed: Crossbred Canine/dog (2), Domestic Shorthair (2), Bulldog (1).

Most co-reported drugs: Praziquantel (2 reports), Imidacloprid + Moxidectin (1 reports), Enrofloxacin (1 reports), Swine Influenza Vaccine (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.