Uveitis

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VeDDRA Code: 435

264 adverse event reports referencing this reaction

264
Total Reports
41
Deaths
1550.0%
Death Rate

Species Most Affected

Dog 210
Cat 45
Horse 8
Cattle 1

Breeds Most Affected

Domestic Shorthair 19
Retriever - Labrador 18
Crossbred Canine/dog 18
Domestic (unspecified) 8
Schnauzer (unspecified) 7
Chihuahua 7
Shih Tzu 7
Schnauzer - Miniature 7
Terrier - Yorkshire 6
Poodle (unspecified) 5

Associated Drugs

Carprofen 20
Moxidectin 16
Recombinant Human Insulin 15
Oclacitinib Maleate 15
Milbemycin Oxime + Spinosad 14
Spinosad 13
Trilostane 13
Prednisone 11
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 10
Insulin Injectable Vial 10
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 10
Enrofloxacin 9
Doxycycline 9
Polysulfated Glycosaminoglycan 9
Gabapentin 9
Frunevetmab 9
Cefovecin 8
Maropitant Citrate 7
Fluralaner Chew Tablets 7
Robenacoxib 7

Data Summary

Metric Value
Total reports referencing reaction 264
Reports with fatal outcome 41
Case-fatality rate (reported events) 1550.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 435.

Uveitis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 264 adverse event reports that reference Uveitis as a reaction term, including 41 reports with a death outcome — a 1550.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 435, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Uveitis appears most frequently in reports for Dog (210 reports), Cat (45 reports), Horse (8 reports) — with Dog dominating at 210 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (19), Retriever - Labrador (18), Crossbred Canine/dog (18). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Uveitis are Carprofen (20 reports), Moxidectin (16 reports), Recombinant Human Insulin (15 reports), Oclacitinib Maleate (15 reports), with Carprofen appearing alongside this reaction in 20 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial