Pyloric ulcer

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VeDDRA Code: 1717

87 adverse event reports referencing this reaction

87
Total Reports
32
Deaths
3680.0%
Death Rate

Species Most Affected

Dog 72
Horse 11
Cat 3
Cattle 1

Breeds Most Affected

Retriever - Labrador 26
Retriever - Golden 7
Rottweiler 7
Boxer (German Boxer) 6
Horse (unknown) 4
Crossbred Canine/dog 3
Dog (unknown) 3
Mastiff 2
Quarter Horse 2
Domestic Shorthair 2

Associated Drugs

Deracoxib 26
Carprofen 23
Firocoxib 12
Omeprazole 37% Oral Paste 11
Meloxicam 9
Firocoxib 227 Mg Chewable 6
Maropitant Citrate 6
Buprenorphine 5
Propofol 5
Gabapentin 5
Isoflurane 5
Midazolam 4
Atropine 4
Milbemycin Oxime + Spinosad 3
Anesthetic 3
Enrofloxacin 3
Lidocaine 3
Ketamine 3
Bordetella Bronchiseptica Vaccine, Avirulent Live Culture 2
Tramadol 2

Data Summary

Metric Value
Total reports referencing reaction 87
Reports with fatal outcome 32
Case-fatality rate (reported events) 3680.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1717.

Pyloric ulcer Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 87 adverse event reports that reference Pyloric ulcer as a reaction term, including 32 reports with a death outcome — a 3680.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1717, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Pyloric ulcer appears most frequently in reports for Dog (72 reports), Horse (11 reports), Cat (3 reports) — with Dog dominating at 72 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (26), Retriever - Golden (7), Rottweiler (7). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Pyloric ulcer are Deracoxib (26 reports), Carprofen (23 reports), Firocoxib (12 reports), Omeprazole 37% Oral Paste (11 reports), with Deracoxib appearing alongside this reaction in 26 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial