Reaction profile

The FDA adverse-event record for faecal impaction

42 FDA adverse-event reports reference faecal impaction (VeDDRA 266). See the species, breeds, and drugs most associated with it below.

42
reports citing this reaction
33.3%
death-coded share
Horse
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
42
Total Reports
14
Deaths
33.3%
Death Rate

Species Most Affected

Horse 19
Dog 11
Cat 10
Pig 1
Turkey 1

Breeds Most Affected

Domestic Shorthair 6
Quarter Horse 4
Arab 3
Horse (unknown) 3
Domestic Longhair 2
Terrier - Jack Russell 2
Maltese 2
Domestic Mediumhair 1
Retriever - Labrador 1
Setter - English 1

Associated Drugs

Milbemycin Oxime + Spinosad 6
Lufenuron + Milbemycin Oxime 3
Enema 3
Pergolide Mesylate 3
Praziquantel; Moxidectin 3
Robenacoxib 3
Emodepside + Praziquantel 2
Fluralaner Chew Tablets 2
Maropitant Citrate 2
Fluralaner Spot-On Solution 2
Flunixin Meglumine Injectable 2
Yf-Wn Chimera Havl Adj Kv Gmo 2
Imidacloprid + Moxidectin 1
Trimethoprim/ Sulfadimethoxine Labeled For Horses 1
Ivermectin 1
Cephalexin 1
Levothyroxine Sodium 1
Ivermectin 1.87% Parziquantel 14.03% 1
Narasin 1
Chlortetracycline 1

Faecal impaction Reaction Insights

42 reports name Faecal impaction; 14 recorded a death outcome (33.3% of reported events, not a population-level mortality rate). VeDDRA code: 266.

By species: Horse (19 reports), Dog (11 reports), Cat (10 reports). By breed: Domestic Shorthair (6), Quarter Horse (4), Arab (3).

Most co-reported drugs: Milbemycin Oxime + Spinosad (6 reports), Lufenuron + Milbemycin Oxime (3 reports), Enema (3 reports), Pergolide Mesylate (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.