Phlebitis

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VeDDRA Code: 241

22 adverse event reports referencing this reaction

22
Total Reports
2
Deaths
910.0%
Death Rate

Species Most Affected

Dog 19
Cat 2
Unknown 1

Breeds Most Affected

Retriever - Labrador 4
Crossbred Canine/dog 2
Dog (unknown) 2
Coonhound (unspecified) 1
Corgi - Welsh Pembroke 1
Unknown 1
Shih Tzu 1
Shepherd Dog - Australian 1
Shepherd Dog (unspecified) 1
Rottweiler 1

Associated Drugs

Maropitant Citrate 7
Carprofen 4
Metronidazole 4
Enrofloxacin 4
Meloxicam 4
Hydromorphone 4
Device: Catheter 3
Midazolam 3
Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate, Potassium Chloride, Magnesium Chloride 3
Water, Sodium Chloride 3
Heparin 3
Fentanyl 3
Intravenous Catheter 3
Famotidine 2
Amoxicillin 2
Propofol 2
Isoflurane 2
Milbemycin Oxime And Lufenuron 2
Buprenorphine 2
Fuzapladib Sodium 2

Data Summary

Metric Value
Total reports referencing reaction 22
Reports with fatal outcome 2
Case-fatality rate (reported events) 910.0%
Species observed 3
Breeds observed 17
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 241.

Phlebitis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 22 adverse event reports that reference Phlebitis as a reaction term, including 2 reports with a death outcome — a 910.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 241, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Phlebitis appears most frequently in reports for Dog (19 reports), Cat (2 reports), Unknown (1 reports) — with Dog dominating at 19 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (4), Crossbred Canine/dog (2), Dog (unknown) (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Phlebitis are Maropitant Citrate (7 reports), Carprofen (4 reports), Metronidazole (4 reports), Enrofloxacin (4 reports), with Maropitant Citrate appearing alongside this reaction in 7 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial