Reaction profile

The FDA adverse-event record for cataract

619 FDA reports name cataract, a high-volume reaction in the CVM extract (VeDDRA 444). Plate stamps and neighbourhood peers follow.

#563 of 2,481
by report volume (all reactions)
619
reports citing this reaction
12.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cataract has 619 reports now versus 614 in that prior snapshot: 5 more (0.8%).

Report change
+5
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cataract changes

FDA AER · VeDDRA plate

Code 444 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 619 reports
  • DEATH-ELEV 12.0%
  • UPPER-Q #563/2481
  • PHOTO-FINISH Red eye
  • SPECIES-DOG Dog · 590
  • DRUG-LEAD Trilostane · 120
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Red eye (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Cataract

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Increased salivation · near622Head tilt - neurologi… · near621Cataract · this reaction619Red eye · near619Enlarged liver · near617Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Cataract

What the FDA AER plate says about Cataract

Signature read: 619 reports place Cataract in the upper third of FDA AER volume (#563 of 2,481). Report volume is upper-third scale: 619 named reports in the openFDA extract. 74 of 619 reports were death-coded (12.0% of named reports, not a population mortality rate). Nearest volume peer: Red eye (±0 reports). Lead species Dog (590). Lead co-reported drug Trilostane (120).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 590
Cat 23
Horse 2
Rabbit 1
Human 1
Cattle 1
Donkey 1

Breeds Most Affected

Crossbred Canine/dog 59
Retriever - Labrador 47
Chihuahua 33
Terrier - Yorkshire 32
Shih Tzu 30
Pinscher - Miniature 22
Schnauzer - Miniature 21
Maltese 20
Bichon Frise 19
Dog (unknown) 15

Associated Drugs

Trilostane 120
Milbemycin Oxime + Spinosad 83
Insulin Injectable Vial 71
Recombinant Human Insulin 69
Spinosad 51
Fluralaner Chew Tablets 32
Oclacitinib Maleate 27
Insulin 23
Carprofen 18
Ivermectin 18
Maropitant Citrate 18
Gabapentin 18
Grapiprant 16
Bordetella Vaccine 14
Prednisone 14
Milbemycin Oxime + Praziquantel 14
Bedinvetmab 14
Pimobendan 13
Cyclosporine 12
Porcine Insulin 12

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Cataract, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (619 here).

Similar death-coded share

Nearest other reactions by death-coded share (12.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cataract (#563 of 2,481 by report volume); death-coded 12.0%. PlainBreed reaction plate · report volume stamp 619 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →