Reaction profile

The FDA adverse-event record for cataract

599 FDA adverse-event reports reference cataract (VeDDRA 444). See the species, breeds, and drugs most associated with it below.

599
reports citing this reaction
12.0%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
599
Total Reports
72
Deaths
12.0%
Death Rate

Species Most Affected

Dog 571
Cat 22
Horse 2
Rabbit 1
Human 1
Cattle 1
Donkey 1

Breeds Most Affected

Crossbred Canine/dog 55
Retriever - Labrador 47
Terrier - Yorkshire 32
Chihuahua 32
Shih Tzu 30
Pinscher - Miniature 22
Schnauzer - Miniature 21
Maltese 20
Bichon Frise 17
Dog (unknown) 15

Associated Drugs

Trilostane 118
Milbemycin Oxime + Spinosad 82
Insulin Injectable Vial 70
Recombinant Human Insulin 69
Spinosad 51
Fluralaner Chew Tablets 32
Oclacitinib Maleate 27
Insulin 19
Carprofen 18
Ivermectin 16
Grapiprant 16
Gabapentin 15
Prednisone 14
Maropitant Citrate 14
Cyclosporine 12
Porcine Insulin 12
Bedinvetmab 12
Milbemycin Oxime 11
Cyclosporine A 11
Bordetella Vaccine 11

Cataract Reaction Insights

599 reports name Cataract; 72 recorded a death outcome (12.0% of reported events, not a population-level mortality rate). VeDDRA code: 444.

By species: Dog (571 reports), Cat (22 reports), Horse (2 reports). By breed: Crossbred Canine/dog (55), Retriever - Labrador (47), Terrier - Yorkshire (32).

Most co-reported drugs: Trilostane (118 reports), Milbemycin Oxime + Spinosad (82 reports), Insulin Injectable Vial (70 reports), Recombinant Human Insulin (69 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.