Reaction profile

The FDA adverse-event record for neurogenic keratoconjunctivitis sicca (kcs)

154 FDA adverse-event reports reference neurogenic keratoconjunctivitis sicca (kcs) (VeDDRA 2866). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1171 of 2,481
by report volume (all reactions)
154
reports citing this reaction
5.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Neurogenic keratoconjunctivitis sicca (KCS) has 154 reports now versus 138 in that prior snapshot: 16 more (11.6%).

Report change
+16
Death-coded reports
+1
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Neurogenic keratoconjunctivitis sicca (KCS) changes

FDA AER · VeDDRA plate

Code 2866 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 154 reports
  • DEATH-PAR 5.8%
  • MID-PACK #1171/2481
  • PHOTO-FINISH Folliculitis
  • SPECIES-DOG Dog · 154
  • DRUG-LEAD Florfenicol + Mom… · 102
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Folliculitis (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Neurogenic keratoconjunctivitis sicca

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Folliculitis · near154Lot # and/or Expirati… · near154Neurogenic keratoconj… · thi…154Third eyelid prolapse · near154High ionized calcium… · near153Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Neurogenic keratoconjunctivitis sicca (KCS)

Neurogenic keratoconjunctivitis sicca (KCS): low death-coded share in the FDA AER plate

Signature read: Neurogenic keratoconjunctivitis sicca (KCS)'s 5.8% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 9 of 154 reports (5.8% of named reports). Nearest volume peer: Folliculitis (±0 reports). Lead species Dog (154). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (102).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 154

Breeds Most Affected

Shih Tzu 18
Chihuahua 11
Terrier - Rat 9
Dachshund (unspecified) 9
Terrier - Yorkshire 8
Bulldog - French 7
Dog (unknown) 7
Retriever - Golden 6
Maltese 6
Crossbred Canine/dog 5

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 102
Maropitant Citrate 33
Prednisone 21
Pilocarpine 20
Cyclosporine (Ophthalmic) 18
Enrofloxacin 16
Florfenicol, Terbinafine, Betamethasone Acetate 15
Ofloxacin 14
Gabapentin 14
Carprofen 12
Ear Cleaner (Unknown) 11
Bordetella Vaccine 11
Cefovecin Sodium 10
Pilocarpine Ophthalmic 10
Florfenicol, Terbinafine, Mometasone Furoate 10
Ear Cleaner 9
Cyclosporine 8
Eye Lubricant 7
Florfenicol,Mometasone Furoate,Terbinafine Hydrochloride 7
Florfenicol, Terbinafine Hcl, Mometasone Furoate 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Neurogenic keratoconjunctivitis sicca (KCS), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (5.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Neurogenic keratoconjunctivitis sicca (KCS) (#1171 of 2,481 by report volume); death-coded 5.8%. PlainBreed reaction plate · death-coded share stamp 5.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →