Reaction profile

The FDA adverse-event record for hair loss nos

3,080 FDA adverse-event reports reference hair loss nos (VeDDRA 1507). See the species, breeds, and drugs most associated with it below.

3,080
reports citing this reaction
3.1%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
3,080
Total Reports
94
Deaths
3.1%
Death Rate

Species Most Affected

Dog 2,075
Cat 687
Cattle 284
Horse 18
Ferret 6
Human 4
Unknown 2
Other Bovine 1
Donkey 1
Pig 1

Breeds Most Affected

Domestic Shorthair 387
Retriever - Labrador 232
Crossbred Canine/dog 149
Chihuahua 125
Dog (unknown) 112
Shepherd Dog - German 109
Aberdeen Angus 98
Retriever - Golden 85
Cat (unknown) 69
Pit Bull 63

Associated Drugs

Milbemycin Oxime + Spinosad 458
Afoxolaner 224
Trilostane 171
Selamectin 165
Spinosad 163
Oclacitinib Maleate 163
Nitenpyram 131
Frunevetmab 124
Ivermectin 0.5% Pour-On Topical Solution 111
Portech App Gun 65 Ml Ivomec/Eprinex 99
Selamectin;Sarolaner 99
Fluralaner Chew Tablets 98
Prednisone 91
Fluralaner Spot-On Solution 82
Pyrantel Pamoate;Sarolaner 77
Bedinvetmab 73
Fluralaner 13.64% 12-Week Chew 71
Ivermectin 65
Ivermectin + Pyrantel As Pamoate Salt 65
Moxidectin 64

Hair loss NOS Reaction Insights

3,080 reports name Hair loss NOS; 94 recorded a death outcome (3.1% of reported events, not a population-level mortality rate). VeDDRA code: 1507.

By species: Dog (2,075 reports), Cat (687 reports), Cattle (284 reports). By breed: Domestic Shorthair (387), Retriever - Labrador (232), Crossbred Canine/dog (149).

Most co-reported drugs: Milbemycin Oxime + Spinosad (458 reports), Afoxolaner (224 reports), Trilostane (171 reports), Selamectin (165 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.