Reaction profile

The FDA adverse-event record for peripheral neuropathy

50 FDA reports name peripheral neuropathy, a lower-volume reaction in the CVM extract (VeDDRA 1689). Plate stamps and neighbourhood peers follow.

#1739 of 2,481
by report volume (all reactions)
50
reports citing this reaction
22.0%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Peripheral neuropathy has 50 reports now versus 49 in that prior snapshot: 1 more (2.0%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Peripheral neuropathy changes

FDA AER · VeDDRA plate

Code 1689 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 50 reports
  • DEATH-HOT 22.0%
  • MID-PACK #1739/2481
  • PHOTO-FINISH Application site papu…
  • SPECIES-CAT Cat · 24
  • DRUG-LEAD Bedinvetmab · 10
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site papule (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Peripheral neuropathy

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site papu… · near50Bounding pulse · near50Device-related infect… · near50Eyeball protrusion · near50Peripheral neuropathy · this…50Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Peripheral neuropathy

What the FDA AER plate says about Peripheral neuropathy

Signature read: 50 reports place Peripheral neuropathy in the lower third of FDA AER volume (#1739 of 2,481). Report volume is lower-third scale: 50 named reports in the openFDA extract. 11 of 50 reports were death-coded (22.0% of named reports, not a population mortality rate). Nearest volume peer: Application site papule (±0 reports). Lead species Cat (24). Lead co-reported drug Bedinvetmab (10).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 24
Dog 21
Horse 4
Human 1

Breeds Most Affected

Domestic Shorthair 18
Retriever - Labrador 4
Collie - Border 2
Terrier - Bull - American Pit 2
Crossbred Canine/dog 2
Siberian Husky 2
Horse (unknown) 2
Domestic Longhair 1
Terrier - Yorkshire 1
Unknown 1

Associated Drugs

Bedinvetmab 10
Velagliflozin Proline Monohydrate 9
Frunevetmab 6
Gabapentin 6
Insulin Injectable Vial 4
Prednisone 4
Isoflurane 4
Doxycycline 3
Ketamine 3
Milbemycin Oxime + Spinosad 2
Butorphanol Tartrate 2
Cefovecin 2
Meloxicam 2
Oclacitinib Maleate 2
Moxidectin 2
Milbemycin Oxime 2
Dexamethasone 2
Galliprant 2
Marbofloxacin 2
Unspecified Keppra 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Peripheral neuropathy, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (50 here).

Similar death-coded share

Nearest other reactions by death-coded share (22.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Peripheral neuropathy (#1739 of 2,481 by report volume); death-coded 22.0%. PlainBreed reaction plate · report volume stamp 50 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →