Reaction profile

The FDA adverse-event record for peripheral neuropathy

44 FDA adverse-event reports reference peripheral neuropathy (VeDDRA 1689). See the species, breeds, and drugs most associated with it below.

44
reports citing this reaction
22.7%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
44
Total Reports
10
Deaths
22.7%
Death Rate

Species Most Affected

Dog 20
Cat 19
Horse 4
Human 1

Breeds Most Affected

Domestic Shorthair 14
Retriever - Labrador 4
Collie - Border 2
Terrier - Bull - American Pit 2
Siberian Husky 2
Crossbred Canine/dog 2
Horse (unknown) 2
Domestic Longhair 1
Terrier - Yorkshire 1
Spaniel (unspecified) 1

Associated Drugs

Bedinvetmab 9
Velagliflozin Proline Monohydrate 7
Gabapentin 6
Isoflurane 4
Frunevetmab 4
Insulin Injectable Vial 3
Prednisone 3
Doxycycline 3
Ketamine 3
Milbemycin Oxime + Spinosad 2
Butorphanol Tartrate 2
Cefovecin 2
Meloxicam 2
Oclacitinib Maleate 2
Moxidectin 2
Milbemycin Oxime 2
Dexamethasone 2
Marbofloxacin 2
Unspecified Keppra 2
Unspecified Zonisamide 2

Peripheral neuropathy Reaction Insights

44 reports name Peripheral neuropathy; 10 recorded a death outcome (22.7% of reported events, not a population-level mortality rate). VeDDRA code: 1689.

By species: Dog (20 reports), Cat (19 reports), Horse (4 reports). By breed: Domestic Shorthair (14), Retriever - Labrador (4), Collie - Border (2).

Most co-reported drugs: Bedinvetmab (9 reports), Velagliflozin Proline Monohydrate (7 reports), Gabapentin (6 reports), Isoflurane (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.