Reaction profile

The FDA adverse-event record for lack of efficacy (virus) - distemper virus

16 FDA reports name lack of efficacy (virus) - distemper virus, a lower-volume reaction in the CVM extract (VeDDRA 2551). Plate stamps and neighbourhood peers follow.

#2281 of 2,481
by report volume (all reactions)
16
reports citing this reaction
75.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (virus) - distemper virus has 16 reports now versus 16 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (virus) - distemper virus changes

FDA AER · VeDDRA plate

Code 2551 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 16 reports
  • DEATH-HOT 75.0%
  • BOTTOM-DECILE #2281/2481
  • PHOTO-FINISH Abdominal transudate
  • SPECIES-DOG Dog · 16
  • DRUG-LEAD Canine Adenovirus… · 6
  • DESK-WIDE 13 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abdominal transudate (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of efficacy - distemper virus

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abdominal transudate · near16Abnormal rectal palpa… · near16AMMONIA INCREASED, BL… · near16Application site gran… · near16Lack of efficacy (vir… · thi…16Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of efficacy (virus) - distemper virus

Lack of efficacy (virus) - distemper virus: high death-coded share in the FDA AER plate

Signature read: Lack of efficacy (virus) - distemper virus's 75.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 16 named reports in the openFDA extract. Death-coded share is upper-third: 12 of 16 reports (75.0% of named reports). Nearest volume peer: Abdominal transudate (±0 reports). Lead species Dog (16). Lead co-reported drug Canine Adenovirus Type 2,Toronto A/26/61,Live + Canine Distemper,Vcp258,Vector + Canine Parainfluenza Virus,D-008,Live + Canine Parvovirus,780916,Live (6).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 16

Breeds Most Affected

Retriever - Labrador 2
Rottweiler 2
Crossbred Canine/dog 2
Chihuahua 1
Pug 1
Collie - Border 1
Coonhound - Bluetick 1
Spitz - German Pomeranian 1
Mountain Dog - Bernese 1
Siberian Husky 1

Associated Drugs

Canine Adenovirus Type 2,Toronto A/26/61,Live + Canine Distemper,Vcp258,Vector + Canine Parainfluenza Virus,D-008,Live + Canine Parvovirus,780916,Live 6
Enrofloxacin 4
Fenbendazol Granules 4
Ivermectin 3
Levetiracetam 3
Canine Da2Ppv (Orig S-P Us) Lv 3
Imrab 1 - 1905.21 2
Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str 2
Metronidazole 2
Diazepam 2
Fenbendazole 2
Fenbendazol Suspension 2
Canine Bb/Pi3/Adeno 2 Lv/Lb 2
Ivermectin + Pyrantel As Pamoate Salt 2
Afoxolaner 2
Imrab 1 - 1905.25 1
Ponazuril 1
Dexmedetomidine Hydrochloride 1
Canine Rabies Vaccine 1
Methocarbamol 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (virus) - distemper virus (#2281 of 2,481 by report volume); death-coded 75.0%. PlainBreed reaction plate · death-coded share stamp 75.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →