Reaction profile

The FDA adverse-event record for impaired proprioception

270 FDA adverse-event reports reference impaired proprioception (VeDDRA 1156). See the species, breeds, and drugs most associated with it below.

270
reports citing this reaction
18.9%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
270
Total Reports
51
Deaths
18.9%
Death Rate

Species Most Affected

Dog 243
Cat 26
Horse 1

Breeds Most Affected

Retriever - Labrador 34
Domestic Shorthair 19
Retriever - Golden 15
Shepherd Dog - German 11
Chihuahua 11
Crossbred Canine/dog 10
Terrier - Bull - American Pit 9
Terrier (unspecified) 8
Collie - Border 7
Shih Tzu 7

Associated Drugs

Bedinvetmab 101
Gabapentin 41
Carprofen 29
Milbemycin Oxime + Spinosad 22
Maropitant Citrate 19
Sarolaner 18
Pyrantel Pamoate;Sarolaner 14
Oclacitinib Maleate 13
Galliprant 13
Prednisone 12
Moxidectin 11
Grapiprant 11
Spinosad 9
Afoxolaner 9
Melarsomine Dihydrochloride 9
Frunevetmab 9
Tramadol 7
Selamectin 7
Meloxicam 7
Fluralaner Chew Tablets 7

Impaired proprioception Reaction Insights

270 reports name Impaired proprioception; 51 recorded a death outcome (18.9% of reported events, not a population-level mortality rate). VeDDRA code: 1156.

By species: Dog (243 reports), Cat (26 reports), Horse (1 reports). By breed: Retriever - Labrador (34), Domestic Shorthair (19), Retriever - Golden (15).

Most co-reported drugs: Bedinvetmab (101 reports), Gabapentin (41 reports), Carprofen (29 reports), Milbemycin Oxime + Spinosad (22 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.