Reaction profile

The FDA adverse-event record for decreased haematocrit

771 FDA adverse-event reports reference decreased haematocrit (VeDDRA 2853). See the species, breeds, and drugs most associated with it below.

771
reports citing this reaction
28.0%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
771
Total Reports
216
Deaths
28.0%
Death Rate

Species Most Affected

Dog 520
Cat 251

Breeds Most Affected

Domestic Shorthair 162
Retriever - Labrador 75
Crossbred Canine/dog 36
Retriever - Golden 35
Domestic Longhair 24
Shepherd Dog - German 19
Cat (unknown) 17
Chihuahua 16
Shih Tzu 15
Domestic Mediumhair 15

Associated Drugs

Maropitant Citrate 116
Bedinvetmab 95
Gabapentin 66
Prednisone 64
Ilunocitinib 62
Carprofen 61
Fluid Therapy 54
Buprenorphine 50
Enrofloxacin 49
Oclacitinib Maleate 49
Trilostane 48
Afoxolaner 39
Bexagliflozin 39
Verdinexor 38
Molidustat 38
Metronidazole 35
Mirtazapine 32
Frunevetmab 30
Doxycycline 28
Lotilaner 28

Decreased haematocrit Reaction Insights

771 reports name Decreased haematocrit; 216 recorded a death outcome (28.0% of reported events, not a population-level mortality rate). VeDDRA code: 2853.

By species: Dog (520 reports), Cat (251 reports). By breed: Domestic Shorthair (162), Retriever - Labrador (75), Crossbred Canine/dog (36).

Most co-reported drugs: Maropitant Citrate (116 reports), Bedinvetmab (95 reports), Gabapentin (66 reports), Prednisone (64 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.