Decreased haematocrit

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VeDDRA Code: 2853

771 adverse event reports referencing this reaction

771
Total Reports
216
Deaths
2800.0%
Death Rate

Species Most Affected

Dog 520
Cat 251

Breeds Most Affected

Domestic Shorthair 162
Retriever - Labrador 75
Crossbred Canine/dog 36
Retriever - Golden 35
Domestic Longhair 24
Shepherd Dog - German 19
Cat (unknown) 17
Chihuahua 16
Shih Tzu 15
Domestic Mediumhair 15

Associated Drugs

Maropitant Citrate 116
Bedinvetmab 95
Gabapentin 66
Prednisone 64
Ilunocitinib 62
Carprofen 61
Fluid Therapy 54
Buprenorphine 50
Enrofloxacin 49
Oclacitinib Maleate 49
Trilostane 48
Afoxolaner 39
Bexagliflozin 39
Verdinexor 38
Molidustat 38
Metronidazole 35
Mirtazapine 32
Frunevetmab 30
Doxycycline 28
Lotilaner 28

Data Summary

Metric Value
Total reports referencing reaction 771
Reports with fatal outcome 216
Case-fatality rate (reported events) 2800.0%
Species observed 2
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2853.

Decreased haematocrit Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 771 adverse event reports that reference Decreased haematocrit as a reaction term, including 216 reports with a death outcome — a 2800.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2853, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Decreased haematocrit appears most frequently in reports for Dog (520 reports), Cat (251 reports) — with Dog dominating at 520 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (162), Retriever - Labrador (75), Crossbred Canine/dog (36). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Decreased haematocrit are Maropitant Citrate (116 reports), Bedinvetmab (95 reports), Gabapentin (66 reports), Prednisone (64 reports), with Maropitant Citrate appearing alongside this reaction in 116 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial