Reaction profile

The FDA adverse-event record for retinal haemorrhage

61 FDA adverse-event reports reference retinal haemorrhage (VeDDRA 467). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1651 of 2,481
by report volume (all reactions)
61
reports citing this reaction
21.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Retinal haemorrhage has 61 reports now versus 56 in that prior snapshot: 5 more (8.9%).

Report change
+5
Death-coded reports
+0
Death-coded share
−1.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Retinal haemorrhage changes

FDA AER · VeDDRA plate

Code 467 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 61 reports
  • DEATH-HOT 21.3%
  • MID-PACK #1651/2481
  • PHOTO-FINISH Injection site numbne…
  • SPECIES-DOG Dog · 38
  • DRUG-LEAD Trilostane · 7
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Injection site numbness (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Retinal haemorrhage

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Injection site numbne… · near61Intussusception · near61Oral pain · near61Paraplegia · near61Retinal haemorrhage · this r…61Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Retinal haemorrhage

What the FDA AER plate says about Retinal haemorrhage

Signature read: report volume at 61 (#1651 of 2,481) is the standout scale stamp on Retinal haemorrhage. Report volume sits in the middle third of the reaction corpus. 13 of 61 reports were death-coded (21.3% of named reports, not a population mortality rate). Nearest volume peer: Injection site numbness (±0 reports). Lead species Dog (38). Lead co-reported drug Trilostane (7).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 38
Cat 23

Breeds Most Affected

Retriever - Labrador 12
Domestic Shorthair 12
Domestic (unspecified) 3
Shih Tzu 3
Terrier - Jack Russell 3
Crossbred Canine/dog 3
Chihuahua 2
Beagle 2
Ragdoll 2
Domestic Mediumhair 2

Associated Drugs

Trilostane 7
Carprofen 6
Enrofloxacin 4
Bedinvetmab 4
Marbofloxacin 3
Spinosad 3
Ivermectin 3
Moxidectin 3
Cyclosporine A 3
Glucosamine 3
Gabapentin 3
Frunevetmab 3
Prednisone 3
Orbifloxacin 2
Dexmedetomidine Hydrochloride 2
Deracoxib 2
Amlodipine 2
Milbemycin Oxime + Spinosad 2
Oclacitinib Maleate 2
Grapiprant 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Retinal haemorrhage, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (61 here).

Similar death-coded share

Nearest other reactions by death-coded share (21.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Retinal haemorrhage (#1651 of 2,481 by report volume); death-coded 21.3%. PlainBreed reaction plate · report volume stamp 61 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →