Reaction profile

The FDA adverse-event record for uterine disorder nos

52 FDA adverse-event reports reference uterine disorder nos (VeDDRA 2146). See the species, breeds, and drugs most associated with it below.

52
reports citing this reaction
23.1%
death-coded share
Dog
most-affected species
Estriol Tablets
most-associated drug
Verify with FDA CVM →
52
Total Reports
12
Deaths
23.1%
Death Rate

Species Most Affected

Dog 42
Cat 3
Horse 3
Human 2
Other Camelids 1
Pig 1

Breeds Most Affected

Retriever - Labrador 5
Crossbred Canine/dog 4
Unknown 3
Shepherd Dog - German 3
Boxer (German Boxer) 2
Schnauzer - Miniature 2
Chihuahua 2
Spitz - German Pomeranian 2
Retriever - Golden 2
Shih Tzu 2

Associated Drugs

Estriol Tablets 15
Milbemycin Oxime + Spinosad 7
Enrofloxacin 3
Spinosad 2
Maropitant Citrate 2
Isoflurane 2
Selamectin 2
Lotilaner 2
Robenacoxib 2
Trilostane 1
Rabies Vaccine 1
Levothyroxine Sodium 1
Deracoxib 1
Glucosamine/Chondroitin 1
Insulin Injectable Vial 1
Orbifloxacin Oral Suspension 1
Meloxicam 1
Amoxicillin, Clavulanic Acid 1
Fipronil 1
Fluralaner Chew Tablets 1

Uterine disorder NOS Reaction Insights

52 reports name Uterine disorder NOS; 12 recorded a death outcome (23.1% of reported events, not a population-level mortality rate). VeDDRA code: 2146.

By species: Dog (42 reports), Cat (3 reports), Horse (3 reports). By breed: Retriever - Labrador (5), Crossbred Canine/dog (4), Unknown (3).

Most co-reported drugs: Estriol Tablets (15 reports), Milbemycin Oxime + Spinosad (7 reports), Enrofloxacin (3 reports), Spinosad (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.