Reaction profile

The FDA adverse-event record for giant platelets

Name: Giant platelets - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

38 FDA reports name giant platelets, a lower-volume reaction in the CVM extract (VeDDRA 2424). Plate stamps and neighbourhood peers follow.

#1873 of 2,481
by report volume (all reactions): 38
reports citing this reaction: 21.1%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Giant platelets has 38 reports now versus 38 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Giant platelets changes

FDA AER · VeDDRA plate

Code 2424 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 38 reports
DEATH-HOT 21.1%
LOWER-Q #1873/2481
PHOTO-FINISH Clenched jaw
SPECIES-DOG Dog · 34
DRUG-LEAD Oclacitinib Malea… · 8
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Clenched jaw (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Giant platelets

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Giant platelets

What the FDA AER plate says about Giant platelets

Signature read: 38 reports place Giant platelets in the lower third of FDA AER volume (#1873 of 2,481). Report volume is lower-third scale: 38 named reports in the openFDA extract. 8 of 38 reports were death-coded (21.1% of named reports, not a population mortality rate). Nearest volume peer: Clenched jaw (±0 reports). Lead species Dog (34). Lead co-reported drug Oclacitinib Maleate (8).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 34

Cat 4

Breeds Most Affected

Schnauzer - Miniature 3

Retriever - Golden 3

Retriever - Labrador 3

Pug 2

Spaniel - King Charles Cavalier 2

Boxer (German Boxer) 2

Spaniel (unspecified) 2

Cat (unknown) 1

Bichon Frise 1

Shih Tzu 1

Associated Drugs

Oclacitinib Maleate 8

Maropitant Citrate 3

Deracoxib 3

Estriol Tablets 3

Cephalexin 3

Anti-Il31 Mab Mcs Lot #1283563 3

Famotidine 3

Cyclosporine 2

Afoxolaner 2

Dexmedetomidine Hydrochloride 2

Butorphanol 2

Carprofen 2

Milbemycin Oxime + Praziquantel 2

Moxidectin 2

Trilostane 2

Verdinexor 2

Diphenhydramine 2

Bedinvetmab 2

Gabapentin 2

Methocarbamol 2

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Giant platelets (#1873 of 2,481 by report volume); death-coded 21.1%. PlainBreed reaction plate · report volume stamp 38 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →