Polyarthropathy NOS (see also PT Immune-mediated polyarthropathy)

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VeDDRA Code: 1118

14 adverse event reports referencing this reaction

14
Total Reports
2
Deaths
1430.0%
Death Rate

Species Most Affected

Dog 10
Cat 4

Breeds Most Affected

Crossbred Canine/dog 3
Domestic Shorthair 3
Retriever - Golden 2
Shepherd Dog - German 1
Terrier - Bull - American Pit 1
Terrier (unspecified) 1
Dog (unknown) 1
Rottweiler 1
Domestic Mediumhair 1

Associated Drugs

Bedinvetmab 4
Gabapentin 4
Pyrantel Pamoate;Sarolaner 2
Fluid Therapy 2
Enrofloxacin 2
Robenacoxib 2
Feline Leukemia Vaccine, Killed Virus 2
Rabies Vaccine, Killed Virus 2
Feline Calicivirus + Rhinotracheitis Virus + Panleukopenia Vaccine 2
Frunevetmab 2
Fluralaner 13.64% 12-Week Chew 1
Milbemycin Oxime 1
Propofol 1
Butorphanol Tartrate 1
Carporfen 1
Cefpodoxime Proxetil 1
Pyrantel Pamoate (Pyrantel Embonate) 1
Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 1
Imidacloprid, Flumethrin 1
Afoxolaner + Moxidectin + Pyrantel 1

Data Summary

Metric Value
Total reports referencing reaction 14
Reports with fatal outcome 2
Case-fatality rate (reported events) 1430.0%
Species observed 2
Breeds observed 9
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1118.

Polyarthropathy NOS (see also PT Immune-mediated polyarthropathy) Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 14 adverse event reports that reference Polyarthropathy NOS (see also PT Immune-mediated polyarthropathy) as a reaction term, including 2 reports with a death outcome — a 1430.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1118, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Polyarthropathy NOS (see also PT Immune-mediated polyarthropathy) appears most frequently in reports for Dog (10 reports), Cat (4 reports) — with Dog dominating at 10 entries. Within those species, the breeds most often named alongside this reaction are Crossbred Canine/dog (3), Domestic Shorthair (3), Retriever - Golden (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Polyarthropathy NOS (see also PT Immune-mediated polyarthropathy) are Bedinvetmab (4 reports), Gabapentin (4 reports), Pyrantel Pamoate;Sarolaner (2 reports), Fluid Therapy (2 reports), with Bedinvetmab appearing alongside this reaction in 4 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial