Reaction profile

The FDA adverse-event record for urinary incontinence

4,434 FDA adverse-event reports reference urinary incontinence (VeDDRA 735). See the species, breeds, and drugs most associated with it below.

4,434
reports citing this reaction
15.4%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
4,434
Total Reports
682
Deaths
15.4%
Death Rate

Species Most Affected

Dog 4,149
Cat 278
Horse 2
Human 2
Other Canids 1
Cattle 1
Ferret 1

Breeds Most Affected

Retriever - Labrador 540
Crossbred Canine/dog 287
Shepherd Dog - German 218
Boxer (German Boxer) 154
Dog (unknown) 152
Retriever - Golden 148
Domestic Shorthair 146
Shepherd Dog - Australian 108
Chihuahua 102
Siberian Husky 100

Associated Drugs

Bedinvetmab 1,225
Carprofen 382
Milbemycin Oxime + Spinosad 342
Gabapentin 262
Oclacitinib Maleate 256
Afoxolaner 249
Trilostane 170
Pyrantel Pamoate;Sarolaner 170
Maropitant Citrate 150
Prednisone 145
Fluralaner Chew Tablets 124
Moxidectin 123
Milbemycin Oxime + Praziquantel 116
Spinosad 105
Grapiprant 105
Fluralaner 13.64% 12-Week Chew 105
Anti-Il31 Mab Mcs Lot #1283563 97
Ivermectin + Pyrantel As Pamoate Salt 93
Sarolaner 90
Cefovecin 80

Urinary incontinence Reaction Insights

4,434 reports name Urinary incontinence; 682 recorded a death outcome (15.4% of reported events, not a population-level mortality rate). VeDDRA code: 735.

By species: Dog (4,149 reports), Cat (278 reports), Horse (2 reports). By breed: Retriever - Labrador (540), Crossbred Canine/dog (287), Shepherd Dog - German (218).

Most co-reported drugs: Bedinvetmab (1,225 reports), Carprofen (382 reports), Milbemycin Oxime + Spinosad (342 reports), Gabapentin (262 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.