Reaction profile

The FDA adverse-event record for neutrophilia

5,206 FDA adverse-event reports reference neutrophilia (VeDDRA 168). See the species, breeds, and drugs most associated with it below.

5,206
reports citing this reaction
27.9%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
5,206
Total Reports
1,453
Deaths
27.9%
Death Rate

Species Most Affected

Dog 4,338
Cat 804
Horse 57
Cattle 7

Breeds Most Affected

Retriever - Labrador 536
Domestic Shorthair 480
Crossbred Canine/dog 315
Retriever - Golden 194
Chihuahua 171
Shepherd Dog - German 170
Shih Tzu 150
Terrier - Yorkshire 115
Boxer (German Boxer) 110
Terrier (unspecified) 94

Associated Drugs

Carprofen 602
Maropitant Citrate 580
Milbemycin Oxime + Spinosad 465
Prednisone 319
Afoxolaner 305
Moxidectin 272
Gabapentin 254
Bedinvetmab 251
Oclacitinib Maleate 231
Fluralaner Chew Tablets 231
Spinosad 211
Cefovecin 210
Ivermectin + Pyrantel As Pamoate Salt 201
Meloxicam 198
Trilostane 192
Enrofloxacin 166
Famotidine 157
Metronidazole 156
Doxycycline 144
Buprenorphine 140

Neutrophilia Reaction Insights

5,206 reports name Neutrophilia; 1,453 recorded a death outcome (27.9% of reported events, not a population-level mortality rate). VeDDRA code: 168.

By species: Dog (4,338 reports), Cat (804 reports), Horse (57 reports). By breed: Retriever - Labrador (536), Domestic Shorthair (480), Crossbred Canine/dog (315).

Most co-reported drugs: Carprofen (602 reports), Maropitant Citrate (580 reports), Milbemycin Oxime + Spinosad (465 reports), Prednisone (319 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.