Reaction profile

The FDA adverse-event record for neutrophilia

5,573 FDA reports name neutrophilia, a high-volume reaction in the CVM extract (VeDDRA 168). Plate stamps and neighbourhood peers follow.

#90 of 2,481
by report volume (all reactions)
5,573
reports citing this reaction
27.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Neutrophilia has 5,573 reports now versus 5,419 in that prior snapshot: 154 more (2.8%).

Report change
+154
Death-coded reports
+34
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Neutrophilia changes

FDA AER · VeDDRA plate

Code 168 VOL-HIGH

VOL-HIGH · DEATH-HOT · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-HIGH 5,573 reports
  • DEATH-HOT 27.7%
  • TOP-DECILE #90/2481
  • PHOTO-FINISH Anxiety
  • SPECIES-DOG Dog · 4,592
  • DRUG-LEAD Maropitant Citrate · 661
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Anxiety (±44 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Neutrophilia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Inappropriate urinati… · near5684Agitation · near5667Anxiety · near5617Neutrophilia · this reaction5573Injection site swelli… · near5505Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Neutrophilia

Neutrophilia: high death-coded share in the FDA AER plate

Signature read: 1,542 death-coded reports is a heavy tail count for Neutrophilia in the CVM extract. Report volume is upper-third scale: 5,573 named reports in the openFDA extract. Death-coded share is upper-third: 1,542 of 5,573 reports (27.7% of named reports). Nearest volume peer: Anxiety (±44 reports). Lead species Dog (4,592). Lead co-reported drug Maropitant Citrate (661).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 4,592
Cat 904
Horse 68
Cattle 8
Donkey 1

Breeds Most Affected

Retriever - Labrador 562
Domestic Shorthair 554
Crossbred Canine/dog 339
Retriever - Golden 205
Chihuahua 185
Shepherd Dog - German 184
Shih Tzu 160
Terrier - Yorkshire 121
Boxer (German Boxer) 116
Terrier (unspecified) 102

Associated Drugs

Maropitant Citrate 661
Carprofen 633
Milbemycin Oxime + Spinosad 466
Prednisone 348
Afoxolaner 319
Gabapentin 303
Bedinvetmab 300
Moxidectin 296
Oclacitinib Maleate 245
Fluralaner Chew Tablets 231
Cefovecin 223
Spinosad 211
Meloxicam 209
Ivermectin + Pyrantel As Pamoate Salt 207
Trilostane 202
Enrofloxacin 174
Metronidazole 166
Doxycycline 166
Famotidine 162
Buprenorphine 158

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Neutrophilia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (5,573 here).

Similar death-coded share

Nearest other reactions by death-coded share (27.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Neutrophilia (#90 of 2,481 by report volume); death-coded 27.7%. PlainBreed reaction plate · death-coded report count stamp 1,542 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →