Reaction profile

The FDA adverse-event record for lack of efficacy (fungi) - nos

283 FDA adverse-event reports reference lack of efficacy (fungi) - nos (VeDDRA 2802). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#896 of 2,481
by report volume (all reactions)
283
reports citing this reaction
0.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (fungi) - NOS has 283 reports now versus 252 in that prior snapshot: 31 more (12.3%).

Report change
+31
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (fungi) - NOS changes

FDA AER · VeDDRA plate

Code 2802 VOL-LOW

VOL-LOW · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 283 reports
  • DEATH-RARE 0.7%
  • MID-PACK #896/2481
  • PHOTO-FINISH Cardiomyopathy
  • SPECIES-DOG Dog · 240
  • DRUG-LEAD Genta/Posacon/Mom… · 76
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cardiomyopathy (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Lack of efficacy - NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cardiomyopathy · near283Cognitive disorder NOS · near283Injection site serosa… · near283Lack of efficacy (fun… · thi…283Peeling skin · near283Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of efficacy (fungi) - NOS

Lack of efficacy (fungi) - NOS: low death-coded share in the FDA AER plate

Signature read: Lack of efficacy (fungi) - NOS's 0.7% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 2 of 283 reports (0.7% of named reports). Nearest volume peer: Cardiomyopathy (±0 reports). Lead species Dog (240). Lead co-reported drug Genta/Posacon/Mometa Eardrops (76).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Genta/Posacon/Mometa Eardrops appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 240
Cat 36
Horse 4
Cattle 3

Breeds Most Affected

Crossbred Canine/dog 31
Retriever - Golden 26
Retriever - Labrador 25
Domestic Shorthair 19
Dog (unknown) 12
Pit Bull 11
Poodle (unspecified) 10
Unknown 8
Maltese 6
Shih Tzu 6

Associated Drugs

Genta/Posacon/Mometa Eardrops 76
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 54
Florfenicol + Mometasone Furoate + Terbinafine 48
Itraconazole 28
Ear Cleaner 15
Ear Cleaner (Unknown) 13
Genta/Momet/Clotrim Ear Oint 12
Oclacitinib Maleate 11
Gentamicin Sulfate + Hydrocortisone Aceponate + Miconazole Nitrate 10
Ivermectin + Pyrantel As Pamoate Salt 10
Florfenicol, Terbinafine, Betamethasone Acetate 9
Milbemycin Oxime + Praziquantel 7
Prednisone 7
Orbiflox/Momet/Posaco Eardrops 7
Salicylic Acid 6
Dexamethasone + Neomycin Sulfate + Thiabendazole 5
Anti-Il31 Mab Mcs Lot #1283563 5
Ear Cleansing Solution 5
Ketoconazole + Tris-Edta 5
Oclacitinib 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lack of efficacy (fungi) - NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (283 here).

Similar death-coded share

Nearest other reactions by death-coded share (0.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (fungi) - NOS (#896 of 2,481 by report volume); death-coded 0.7%. PlainBreed reaction plate · death-coded share stamp 0.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →