Reaction profile

The FDA adverse-event record for lack of efficacy (fungi) - nos

197 FDA adverse-event reports reference lack of efficacy (fungi) - nos (VeDDRA 2802). See the species, breeds, and drugs most associated with it below.

197
reports citing this reaction
0.5%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
197
Total Reports
1
Deaths
0.5%
Death Rate

Species Most Affected

Dog 164
Cat 29
Horse 3
Cattle 1

Breeds Most Affected

Retriever - Labrador 17
Domestic Shorthair 16
Crossbred Canine/dog 13
Retriever - Golden 13
Dog (unknown) 10
Pit Bull 10
Poodle (unspecified) 9
Maltese 5
Shih Tzu 5
Bulldog - French 5

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 46
Florfenicol + Mometasone Furoate + Terbinafine 46
Genta/Posacon/Mometa Eardrops 28
Itraconazole 23
Ear Cleaner (Unknown) 13
Florfenicol, Terbinafine, Betamethasone Acetate 9
Ivermectin + Pyrantel As Pamoate Salt 9
Ear Cleaner 9
Gentamicin Sulfate + Hydrocortisone Aceponate + Miconazole Nitrate 7
Prednisone 7
Milbemycin Oxime + Praziquantel 6
Oclacitinib Maleate 6
Salicylic Acid 5
Ear Cleansing Solution 5
Genta/Momet/Clotrim Ear Oint 5
Ketoconazole + Tris-Edta 5
Oclacitinib 4
Lokivetmab 4
Orbiflox/Momet/Posaco Eardrops 4
Dexamethasone + Neomycin Sulfate + Thiabendazole 3

Lack of efficacy (fungi) - NOS Reaction Insights

197 reports name Lack of efficacy (fungi) - NOS; 1 recorded a death outcome (0.5% of reported events, not a population-level mortality rate). VeDDRA code: 2802.

By species: Dog (164 reports), Cat (29 reports), Horse (3 reports). By breed: Retriever - Labrador (17), Domestic Shorthair (16), Crossbred Canine/dog (13).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (46 reports), Florfenicol + Mometasone Furoate + Terbinafine (46 reports), Genta/Posacon/Mometa Eardrops (28 reports), Itraconazole (23 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.