Ileus

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VeDDRA Code: 1086

189 adverse event reports referencing this reaction

189
Total Reports
40
Deaths
2120.0%
Death Rate

Species Most Affected

Dog 153
Cat 23
Horse 11
Other Rodents 1
Unknown 1

Breeds Most Affected

Retriever - Labrador 22
Crossbred Canine/dog 14
Shih Tzu 12
Domestic Shorthair 12
Quarter Horse 7
Retriever - Golden 7
Maltese 6
Terrier - Yorkshire 6
Terrier - Jack Russell 5
Shepherd Dog - German 5

Associated Drugs

Maropitant Citrate 36
Carprofen 29
Milbemycin Oxime + Spinosad 17
Metoclopramide 16
Famotidine 16
Metronidazole 15
Gabapentin 13
Enrofloxacin 12
Deracoxib 11
Sucralfate 9
Fluralaner Chew Tablets 9
Ondansetron 9
Prednisone 8
Propofol 8
Rabies Vaccine 8
Isoflurane 8
Butorphanol 8
Tramadol 7
Omeprazole 7
Fentanyl 7

Data Summary

Metric Value
Total reports referencing reaction 189
Reports with fatal outcome 40
Case-fatality rate (reported events) 2120.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1086.

Ileus Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 189 adverse event reports that reference Ileus as a reaction term, including 40 reports with a death outcome — a 2120.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1086, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Ileus appears most frequently in reports for Dog (153 reports), Cat (23 reports), Horse (11 reports) — with Dog dominating at 153 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (22), Crossbred Canine/dog (14), Shih Tzu (12). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Ileus are Maropitant Citrate (36 reports), Carprofen (29 reports), Milbemycin Oxime + Spinosad (17 reports), Metoclopramide (16 reports), with Maropitant Citrate appearing alongside this reaction in 36 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial