Reaction profile

The FDA adverse-event record for retinal degeneration

156 FDA adverse-event reports reference retinal degeneration (VeDDRA 463). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1165 of 2,481
by report volume (all reactions)
156
reports citing this reaction
11.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Retinal degeneration has 156 reports now versus 154 in that prior snapshot: 2 more (1.3%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Retinal degeneration changes

FDA AER · VeDDRA plate

Code 463 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 156 reports
  • DEATH-ELEV 11.5%
  • MID-PACK #1165/2481
  • PHOTO-FINISH Abnormal necropsy fin…
  • SPECIES-DOG Dog · 125
  • DRUG-LEAD Enrofloxacin · 23
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal necropsy finding (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Retinal degeneration

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Abnormal necropsy fin… · near156Delayed healing · near156Lip disorder NOS · near156Retinal degeneration · this …156Swollen joint · near156Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Retinal degeneration

What the FDA AER plate says about Retinal degeneration

Signature read: death-coded share at 11.5% is the most distinctive outcome stamp on Retinal degeneration. Report volume sits in the middle third of the reaction corpus. 18 of 156 reports were death-coded (11.5% of named reports, not a population mortality rate). Nearest volume peer: Abnormal necropsy finding (±0 reports). Lead species Dog (125). Lead co-reported drug Enrofloxacin (23).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Enrofloxacin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 125
Cat 31

Breeds Most Affected

Domestic Shorthair 17
Crossbred Canine/dog 11
Chihuahua 9
Dachshund (unspecified) 7
Shih Tzu 6
Maltese 6
Schnauzer - Miniature 5
Dog (unknown) 5
Terrier - Yorkshire 4
Collie - Border 4

Associated Drugs

Enrofloxacin 23
Milbemycin Oxime + Spinosad 21
Fluralaner Chew Tablets 18
Spinosad 14
Trilostane 13
Bedinvetmab 10
Carprofen 9
Afoxolaner 8
Moxidectin 7
Oclacitinib Maleate 6
Meloxicam 5
Prednisone 5
Orbifloxacin Oral Suspension 5
Ivermectin + Pyrantel As Pamoate Salt 5
Fluralaner 13.64% 12-Week Chew 5
Maropitant Citrate 4
Ivermectin 4
Pradofloxacin 4
Marbofloxacin 3
Metronidazole 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Retinal degeneration, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (156 here).

Similar death-coded share

Nearest other reactions by death-coded share (11.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Retinal degeneration (#1165 of 2,481 by report volume); death-coded 11.5%. PlainBreed reaction plate · death-coded share stamp 11.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →