Genital tract licking

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VeDDRA Code: 2478

205 adverse event reports referencing this reaction

205
Total Reports
4
Deaths
200.0%
Death Rate

Species Most Affected

Dog 196
Cat 9

Breeds Most Affected

Crossbred Canine/dog 25
Retriever - Labrador 21
Retriever - Golden 11
Shepherd Dog - Australian 10
Shih Tzu 8
Shepherd Dog - German 8
Domestic Shorthair 8
Boxer (German Boxer) 6
Collie - Border 6
Terrier - Yorkshire 5

Associated Drugs

Estriol Tablets 67
Bedinvetmab 34
Carprofen 21
Milbemycin Oxime + Praziquantel 18
Oclacitinib Maleate 15
Gabapentin 14
Pyrantel Pamoate;Sarolaner 12
Phenylpropanolamine Hydrochloride 9
Lotilaner 8
Afoxolaner 7
Trilostane 6
Milbemycin Oxime + Spinosad 5
Anti-Il31 Mab Mcs Lot #1283563 5
Fluralaner 13.64% 12-Week Chew 5
Tramadol 4
Enrofloxacin 4
Grapiprant 4
Phenylpropropanolamine Hcl 4
Incurin 4
Milbemycin Oxime 3

Data Summary

Metric Value
Total reports referencing reaction 205
Reports with fatal outcome 4
Case-fatality rate (reported events) 200.0%
Species observed 2
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2478.

Genital tract licking Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 205 adverse event reports that reference Genital tract licking as a reaction term, including 4 reports with a death outcome — a 200.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2478, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Genital tract licking appears most frequently in reports for Dog (196 reports), Cat (9 reports) — with Dog dominating at 196 entries. Within those species, the breeds most often named alongside this reaction are Crossbred Canine/dog (25), Retriever - Labrador (21), Retriever - Golden (11). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Genital tract licking are Estriol Tablets (67 reports), Bedinvetmab (34 reports), Carprofen (21 reports), Milbemycin Oxime + Praziquantel (18 reports), with Estriol Tablets appearing alongside this reaction in 67 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial