Reaction profile

The FDA adverse-event record for thrombosis

124 FDA adverse-event reports reference thrombosis (VeDDRA 156). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1289 of 2,481
by report volume (all reactions)
124
reports citing this reaction
82.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Thrombosis has 124 reports now versus 123 in that prior snapshot: 1 more (0.8%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Thrombosis changes

FDA AER · VeDDRA plate

Code 156 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 124 reports
  • DEATH-HOT 82.3%
  • MID-PACK #1289/2481
  • PHOTO-FINISH Heart block NOS
  • SPECIES-DOG Dog · 82
  • DRUG-LEAD Milbemycin Oxime… · 11
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Heart block NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Thrombosis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Generalised red spot · near125Heart block NOS · near124Thrombosis · this reaction124Birth defect · near123Hypomagnesaemic condi… · near123Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Thrombosis

Thrombosis: high death-coded share in the FDA AER plate

Signature read: Thrombosis's 82.3% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 102 of 124 reports (82.3% of named reports). Nearest volume peer: Heart block NOS (±0 reports). Lead species Dog (82). Lead co-reported drug Milbemycin Oxime + Spinosad (11).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 82
Cat 32
Horse 5
Cattle 4
Sheep 1

Breeds Most Affected

Domestic Shorthair 24
Retriever - Labrador 8
Retriever - Golden 6
Beagle 5
Shepherd Dog - German 4
Rottweiler 4
Collie - Border 4
Crossbred Canine/dog 3
Domestic Longhair 3
Quarter Horse 2

Associated Drugs

Milbemycin Oxime + Spinosad 11
Maropitant Citrate 11
Carprofen 11
Gabapentin 11
Frunevetmab 9
Bedinvetmab 9
Afoxolaner 7
Trilostane 6
Polysulfated Glycosaminoglycan 5
Deracoxib 5
Tramadol 5
Grapiprant 5
Imidacloprid And Moxidectin 4
Ceftiofur Crystalline Free Acid 4
Midazolam 4
Fluralaner 13.64% 12-Week Chew 4
Enrofloxacin 3
Imidacloprid + Moxidectin 3
Fentanyl 3
Rabies Vaccine 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Thrombosis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (124 here).

Similar death-coded share

Nearest other reactions by death-coded share (82.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Thrombosis (#1289 of 2,481 by report volume); death-coded 82.3%. PlainBreed reaction plate · death-coded share stamp 82.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →