Reaction profile

The FDA adverse-event record for high adrenocorticotropic (acth) hormone

38 FDA reports name high adrenocorticotropic (acth) hormone, a lower-volume reaction in the CVM extract (VeDDRA 2716). Plate stamps and neighbourhood peers follow.

#1874 of 2,481
by report volume (all reactions)
38
reports citing this reaction
0.0%
death-coded share
Horse
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. High adrenocorticotropic (ACTH) hormone has 38 reports now versus 37 in that prior snapshot: 1 more (2.7%).

Report change
+1
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to High adrenocorticotropic (ACTH) hormone changes

FDA AER · VeDDRA plate

Code 2716 VOL-TRACE

VOL-TRACE · DEATH-RARE · LOWER-Q · PHOTO-FINISH · SPECIES-HORSE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 38 reports
  • DEATH-RARE 0.0%
  • LOWER-Q #1874/2481
  • PHOTO-FINISH Clenched jaw
  • SPECIES-HORSE Horse · 33
  • DRUG-LEAD Pergolide Mesylate · 31
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Clenched jaw (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around High adrenocorticotropic hormone

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Clenched jaw · near38Conjunctival reddening · near38Disturbance in attent… · near38Duodenitis · near38High adrenocorticotro… · thi…38Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around High adrenocorticotropic (ACTH) hormone

High adrenocorticotropic (ACTH) hormone: low death-coded share in the FDA AER plate

Signature read: High adrenocorticotropic (ACTH) hormone's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 38 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 38 reports (0.0% of named reports). Nearest volume peer: Clenched jaw (±0 reports). Lead species Horse (33). Lead co-reported drug Pergolide Mesylate (31).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Pergolide Mesylate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Horse 33
Dog 5

Breeds Most Affected

Horse (unknown) 8
Quarter Horse 5
Warmblood (unspecified) 3
Arab 3
Tennessee Walking Horse 2
Holsteiner 2
Thoroughbred 2
Terrier - Bull - American Pit 1
Paso Fino 1
Terrier - Yorkshire 1

Associated Drugs

Pergolide Mesylate 31
Firocoxib 3
Oclacitinib Maleate 1
Insulin Injectable Vial 1
Lotilaner 1
Eye Medication (Unknown) 1
Moxidectin 1
Clodronate Disodium 1
Fluralaner 13.64% 12-Week Chew 1
Ciprofloxacin 1
Ivermectin + Pyrantel As Pamoate Salt 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for High adrenocorticotropic (ACTH) hormone (#1874 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →