Reaction profile
The FDA adverse-event record for cardiac disorder nos
11,478 FDA adverse-event reports reference cardiac disorder nos (VeDDRA 202). See the species, breeds, and drugs most associated with it below.
- 11,478
- reports citing this reaction
- 6.1%
- death-coded share
- Dog
- most-affected species
- Ivermectin + Pyrantel As Pamoate Salt
- most-associated drug
Species Most Affected
Breeds Most Affected
Associated Drugs
Cardiac disorder NOS Reaction Insights
11,478 reports name Cardiac disorder NOS; 701 recorded a death outcome (6.1% of reported events, not a population-level mortality rate). VeDDRA code: 202.
By species: Dog (11,103 reports), Cat (224 reports), Cattle (101 reports). By breed: Retriever - Labrador (2,755), Crossbred Canine/dog (1,388), Shepherd Dog - German (825).
Most co-reported drugs: Ivermectin + Pyrantel As Pamoate Salt (6,766 reports), Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg (1,897 reports), Ivermectin/Pyrantel Pamoate Chewable 136Mcg/326Mg (619 reports), Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg (528 reports).
Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.