Reaction profile

The FDA adverse-event record for skin fibrosarcoma

34 FDA adverse-event reports reference skin fibrosarcoma (VeDDRA 916). See the species, breeds, and drugs most associated with it below.

34
reports citing this reaction
17.6%
death-coded share
Cat
most-affected species
Cefovecin
most-associated drug
Verify with FDA CVM →
34
Total Reports
6
Deaths
17.6%
Death Rate

Species Most Affected

Cat 18
Dog 16

Breeds Most Affected

Domestic Shorthair 12
Siamese 2
Retriever - Labrador 2
Terrier - Bull - Staffordshire 2
Domestic Longhair 2
Retriever - Golden 2
Domestic Mediumhair 2
Bichon Frise 1
Retriever - Flat-coated 1
Poodle - Standard 1

Associated Drugs

Cefovecin 10
Oclacitinib Maleate 8
Robenacoxib 5
Rabies Virus, Kv 4
Buprenorphine 3
Anti-Il31 Mab Mcs Lot #1283563 3
Cyclosporine 3
Cyclosporine A 2
Tylosin Tartrate 2
Meloxicam 2
Maropitant Citrate 2
Enrofloxacin 2
Trilostane 2
Clindamycin 2
Vaccine 1
Lufenuron 1
Prescription Diet (Unspecified) 1
Amoxicillin 1
Mirtazapine 1
Chlorhexidine 1

Skin fibrosarcoma Reaction Insights

34 reports name Skin fibrosarcoma; 6 recorded a death outcome (17.6% of reported events, not a population-level mortality rate). VeDDRA code: 916.

By species: Cat (18 reports), Dog (16 reports). By breed: Domestic Shorthair (12), Siamese (2), Retriever - Labrador (2).

Most co-reported drugs: Cefovecin (10 reports), Oclacitinib Maleate (8 reports), Robenacoxib (5 reports), Rabies Virus, Kv (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.