Reaction profile

The FDA adverse-event record for endocardiosis

Name: Endocardiosis - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

23 FDA reports name endocardiosis, a lower-volume reaction in the CVM extract (VeDDRA 2308). Plate stamps and neighbourhood peers follow.

#2108 of 2,481
by report volume (all reactions): 23
reports citing this reaction: 95.7%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Endocardiosis has 23 reports now versus 22 in that prior snapshot: 1 more (4.5%).

Report change: +1
Death-coded reports: +1
Death-coded share: +0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Endocardiosis changes

FDA AER · VeDDRA plate

Code 2308 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 23 reports
DEATH-HOT 95.7%
LOWER-Q #2108/2481
PHOTO-FINISH Anal oedema
SPECIES-DOG Dog · 22
DRUG-LEAD Bedinvetmab · 7
DESK-WIDE 19 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Anal oedema (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Endocardiosis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Endocardiosis

Endocardiosis: high death-coded share in the FDA AER plate

Signature read: Endocardiosis's 95.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 23 named reports in the openFDA extract. Death-coded share is upper-third: 22 of 23 reports (95.7% of named reports). Nearest volume peer: Anal oedema (±0 reports). Lead species Dog (22). Lead co-reported drug Bedinvetmab (7).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 22

Rabbit 1

Breeds Most Affected

Boxer (German Boxer) 2

Crossbred Canine/dog 2

Spitz - German Pomeranian 2

Terrier - Yorkshire 2

Spaniel - King Charles Cavalier 1

Pit Bull 1

Shepherd Dog - Australian 1

Pointing Dog - Hungarian Short-haired (Vizsla) 1

Griffon - Brussels 1

Rabbit (other) 1

Associated Drugs

Bedinvetmab 7

Maropitant Citrate 3

Meloxicam 3

Grapiprant 2

Levothyroxine 2

Carprofen 2

Pimobendan 2

Moxidectin 2

Metronidazole 2

Furosemide 2

Doxycycline 2

Meclizine 2

Fluralaner 13.64% 12-Week Chew 1

Fuzapladib Sodium 1

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 1

Ketamine Hydrochloride 1

Bravecto 1

Lactulose 1

Subcutaneous Fluids 1

Dexmedetomidine Hydrochloride 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Endocardiosis (#2108 of 2,481 by report volume); death-coded 95.7%. PlainBreed reaction plate · death-coded share stamp 95.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →