Reaction profile

The FDA adverse-event record for increased bowel movements (frequency)

305 FDA adverse-event reports reference increased bowel movements (frequency) (VeDDRA 2231). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#862 of 2,481
by report volume (all reactions)
305
reports citing this reaction
4.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Increased bowel movements (frequency) has 305 reports now versus 302 in that prior snapshot: 3 more (1.0%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Increased bowel movements (frequency) changes

FDA AER · VeDDRA plate

Code 2231 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 305 reports
  • DEATH-LOW 4.6%
  • MID-PACK #862/2481
  • PHOTO-FINISH Increased seizure fre…
  • SPECIES-DOG Dog · 282
  • DRUG-LEAD Milbemycin Oxime… · 27
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Increased seizure frequency (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Increased bowel movements

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Blood in faeces NOS · near307Dermal thickening · near306Swollen tongue · near306Increased bowel movem… · thi…305Increased seizure fre… · near305Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Increased bowel movements (frequency)

Increased bowel movements (frequency): low death-coded share in the FDA AER plate

Signature read: Increased bowel movements (frequency)'s 4.6% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 14 of 305 reports (4.6% of named reports). Nearest volume peer: Increased seizure frequency (±0 reports). Lead species Dog (282). Lead co-reported drug Milbemycin Oxime + Spinosad (27).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 282
Cat 17
Human 4
Horse 2

Breeds Most Affected

Retriever - Labrador 23
Crossbred Canine/dog 23
Dog (unknown) 17
Maltese 13
Chihuahua 12
Shepherd Dog - German 10
Domestic Shorthair 9
Spaniel - King Charles Cavalier 9
Shih Tzu 8
Shepherd Dog - Australian 8

Associated Drugs

Milbemycin Oxime + Spinosad 27
Ivermectin + Pyrantel As Pamoate Salt 25
Fluralaner Chew Tablets 25
Trilostane 19
Milbemycin Oxime + Praziquantel 17
Afoxolaner 14
Oclacitinib Maleate 14
Carprofen 13
Febantel + Praziquantel + Pyrantel Pamoate 12
Pyrantel Pamoate;Sarolaner 12
Fluralaner 13.64% 12-Week Chew 11
Grapiprant 9
Selamectin 8
Lotilaner 8
Bedinvetmab 8
Spinosad 7
Sarolaner 7
Gabapentin 7
Fenbendazol Granules 6
Prednisone 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Increased bowel movements (frequency), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (305 here).

Similar death-coded share

Nearest other reactions by death-coded share (4.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Increased bowel movements (frequency) (#862 of 2,481 by report volume); death-coded 4.6%. PlainBreed reaction plate · death-coded share stamp 4.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →