Reaction profile

The FDA adverse-event record for mastitis nos

180 FDA adverse-event reports reference mastitis nos (VeDDRA 1988). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1088 of 2,481
by report volume (all reactions)
180
reports citing this reaction
36.1%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Mastitis NOS has 180 reports now versus 178 in that prior snapshot: 2 more (1.1%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Mastitis NOS changes

FDA AER · VeDDRA plate

Code 1988 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 180 reports
  • DEATH-HOT 36.1%
  • MID-PACK #1088/2481
  • PHOTO-FINISH Pigmentation disorder
  • SPECIES-CATTLE Cattle · 159
  • DRUG-LEAD Sometribove · 59
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Pigmentation disorder (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Mastitis NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acidic urine · near181Mastitis NOS · this reaction180Pigmentation disorder · near180Prolonged bleeding NOS · near180Slow heart rate · near180Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Mastitis NOS

Mastitis NOS: high death-coded share in the FDA AER plate

Signature read: Mastitis NOS's 36.1% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 65 of 180 reports (36.1% of named reports). Nearest volume peer: Pigmentation disorder (±0 reports). Lead species Cattle (159). Lead co-reported drug Sometribove (59).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 159
Dog 17
Horse 3
Goat 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 108
Cattle (unknown) 20
Cattle (other) 15
Mixed (Cattle) 6
Crossbred Bovine/Cattle 4
Jersey 3
Dog (unknown) 2
Brown Swiss 2
Terrier - Fox Wire 2
Quarter Horse 1

Associated Drugs

Sometribove 59
Monensin Sodium 44
Cloxacillin Benz Intramam Dc 20
Cloxacillin Benzathine 19
Pegbovigrastim 9
Cephapirin Benzathine 6
Bismuth Subnitr Intramammary 6
Bismuth Subnitrate 60% Intramammary 6
Sometribove Zinc Suspension 5
Monensin 4
Carprofen 4
Cephapirin Sodium 3
Milbemycin Oxime + Spinosad 3
Moxidectin 3
Fluralaner 13.64% 12-Week Chew 3
Spinosad 2
Amoxicillin 2
Melengestrol Acetate 2
Ampicillin Trihydrate 2
Lidocaine Hcl 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Mastitis NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (180 here).

Similar death-coded share

Nearest other reactions by death-coded share (36.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Mastitis NOS (#1088 of 2,481 by report volume); death-coded 36.1%. PlainBreed reaction plate · death-coded share stamp 36.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →