Reaction profile

The FDA adverse-event record for convulsion

3,461 FDA reports name convulsion, a high-volume reaction in the CVM extract (VeDDRA 642). Plate stamps and neighbourhood peers follow.

#133 of 2,481
by report volume (all reactions)
3,461
reports citing this reaction
21.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Convulsion has 3,461 reports now versus 3,447 in that prior snapshot: 14 more (0.4%).

Report change
+14
Death-coded reports
+5
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Convulsion changes

FDA AER · VeDDRA plate

Code 642 VOL-MID

VOL-MID · DEATH-HOT · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 3,461 reports
  • DEATH-HOT 21.0%
  • TOP-DECILE #133/2481
  • PHOTO-FINISH Dilated pupils
  • SPECIES-DOG Dog · 2,937
  • DRUG-LEAD Spinosad · 534
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Dilated pupils (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Convulsion

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Convulsion · this reaction3461Dilated pupils · near3461Lateral recumbency · near3455Closure, Abnormal · near3450Lack of efficacy (end… · near3444Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Convulsion

What the FDA AER plate says about Convulsion

Signature read: 728 death-coded reports is a heavy tail count for Convulsion in the CVM extract. Report volume is upper-third scale: 3,461 named reports in the openFDA extract. 728 of 3,461 reports were death-coded (21.0% of named reports, not a population mortality rate). Nearest volume peer: Dilated pupils (±0 reports). Lead species Dog (2,937). Lead co-reported drug Spinosad (534).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 2,937
Cat 414
Horse 43
Cattle 34
Goat 4
Rabbit 4
Pig 4
Sheep 4
Other 3
Human 3

Breeds Most Affected

Crossbred Canine/dog 495
Retriever - Labrador 250
Domestic (unspecified) 241
Chihuahua 143
Dog (unknown) 125
Terrier - Yorkshire 119
Shih Tzu 98
Boxer (German Boxer) 93
Retriever - Golden 79
Dachshund (unspecified) 77

Associated Drugs

Spinosad 534
Selamectin 205
Carprofen 198
Ivermectin, Pyrantel 176
Milbemycin 125
Spinosad, Milbemycin 105
Cyclosporine 94
Afoxolaner 94
Cefovecin Sodium 92
Milbemycin Oxime + Spinosad 89
Moxidectin 77
Meloxicam 73
Milbemycin, Lufenuron 73
Dexmedetomidine Hydrochloride 64
Fluralaner Chew Tablets 64
Propofol 62
Ketamine Hydrochloride 57
Firocoxib 57
Maropitant 50
Ivermectin 48

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Convulsion, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (21.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Convulsion (#133 of 2,481 by report volume); death-coded 21.0%. PlainBreed reaction plate · death-coded report count stamp 728 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →