Reaction profile

The FDA adverse-event record for hypertrophic dilated cardiomyopathy

27 FDA reports name hypertrophic dilated cardiomyopathy, a lower-volume reaction in the CVM extract (VeDDRA 2302). Plate stamps and neighbourhood peers follow.

#2042 of 2,481
by report volume (all reactions)
27
reports citing this reaction
55.6%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hypertrophic dilated cardiomyopathy has 27 reports now versus 26 in that prior snapshot: 1 more (3.8%).

Report change
+1
Death-coded reports
+1
Death-coded share
+1.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hypertrophic dilated cardiomyopathy changes

FDA AER · VeDDRA plate

Code 2302 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 27 reports
  • DEATH-HOT 55.6%
  • LOWER-Q #2042/2481
  • PHOTO-FINISH Abortion spontaneous
  • SPECIES-CAT Cat · 14
  • DRUG-LEAD Isoflurane · 4
  • DESK-WIDE 18 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abortion spontaneous (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Hypertrophic dilated cardiomyopathy

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abortion spontaneous · near27Aplastic anaemia · near27Cyanotic spots/blotch… · near27Cyst rupture NOS · near27Hypertrophic dilated… · this…27Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hypertrophic dilated cardiomyopathy

Hypertrophic dilated cardiomyopathy: high death-coded share in the FDA AER plate

Signature read: Hypertrophic dilated cardiomyopathy's 55.6% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 27 named reports in the openFDA extract. Death-coded share is upper-third: 15 of 27 reports (55.6% of named reports). Nearest volume peer: Abortion spontaneous (±0 reports). Lead species Cat (14). Lead co-reported drug Isoflurane (4).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 14
Dog 13

Breeds Most Affected

Domestic Shorthair 6
Bengal 3
Retriever - Golden 2
Terrier - Yorkshire 2
American Pit Bull Terrier 1
Crossbred Canine/dog 1
Whippet 1
Doberman Pinscher 1
Mastiff (unspecified) 1
Terrier - Bull - American Pit 1

Associated Drugs

Isoflurane 4
Atropine Injection 4
Cefovecin 3
Trazodone 3
Gabapentin 3
Bedinvetmab 3
Robenacoxib 3
Midazolam 3
Alfaxalone 3
Oxygen 3
Epinephrine 3
Trilostane 2
Desoxycortone Pivalate 2
Lactated Ringer&Apos;S Solution 2
Ivermectin + Pyrantel As Pamoate Salt 2
Bexagliflozin 2
Frunevetmab 2
Butorphanol Tartrate 2
Sarolaner 2
Psyllum Husk 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hypertrophic dilated cardiomyopathy (#2042 of 2,481 by report volume); death-coded 55.6%. PlainBreed reaction plate · death-coded share stamp 55.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →