Reaction profile

The FDA adverse-event record for lack of efficacy (bacteria) - anaplasma nos

38 FDA adverse-event reports reference lack of efficacy (bacteria) - anaplasma nos (VeDDRA 2991). See the species, breeds, and drugs most associated with it below.

38
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species
Afoxolaner
most-associated drug
Verify with FDA CVM →
38
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Dog 38

Breeds Most Affected

Dog (unknown) 5
Retriever - Golden 4
Spaniel (unspecified) 3
Retriever - Labrador 3
Crossbred Canine/dog 2
Shepherd Dog - German 2
Shih Tzu 2
Spitz - German Pomeranian 2
Shepherd Dog (unspecified) 2
Alaskan Malamute 2

Associated Drugs

Afoxolaner 22
Pyrantel Pamoate;Sarolaner 10
Lotilaner 10
Milbemycin Oxime + Praziquantel 6
Recombitek Lyme - 2126.R0 3
Borrelia Burgdorferi Bacterin 3
Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 2
Fluralaner 13.64% 12-Week Chew 1
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 1
Leptospira-Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 1
Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19 1
Ivermectin + Pyrantel As Pamoate Salt 1
Unknown Manufacturer Lyme 1
Bordetella Vaccine 1
Milbemycin Oxime, Praziquantel 1
Sarolaner 1
Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Mlv, Borrelia Burgdorferi Bacterin-Lepto Cani-Grippo-Ictero-Pomona Bacterial Extract 1

Lack of efficacy (bacteria) - Anaplasma NOS Reaction Insights

38 reports name Lack of efficacy (bacteria) - Anaplasma NOS; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 2991.

By species: Dog (38 reports). By breed: Dog (unknown) (5), Retriever - Golden (4), Spaniel (unspecified) (3).

Most co-reported drugs: Afoxolaner (22 reports), Pyrantel Pamoate;Sarolaner (10 reports), Lotilaner (10 reports), Milbemycin Oxime + Praziquantel (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.