Reaction profile

The FDA adverse-event record for hyposalivation

10 FDA adverse-event reports reference hyposalivation (VeDDRA 1076). See the species, breeds, and drugs most associated with it below.

10
reports citing this reaction
20.0%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
10
Total Reports
2
Deaths
20.0%
Death Rate

Species Most Affected

Dog 7
Human 1
Cat 1
Horse 1

Breeds Most Affected

Boxer (German Boxer) 1
Terrier - Jack Russell 1
Unknown 1
Poodle - Miniature 1
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) 1
Domestic Shorthair 1
Thoroughbred 1
Borzoi 1
Chihuahua 1
Pit Bull 1

Associated Drugs

Carprofen 1
Firocoxib 1
Ethoxydiglycol + Phytosphingosine 1% + Polyvinylpyrrolidone 1
Febantel + Praziquantel + Pyrantel Pamoate 1
Dexmedetomidine Hydrochloride 1
Atipamezole Hydrochloride 1
Butorphanol Tartrate 1
Dexamethasone + Neomycin Sulfate + Thiabendazole 1
Ivermectin + Praziquantel 1
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 1
Alfaxalone 1
Salicylic Acid 1
Milbemycin Oxime 1
Milbemycin Oxime + Praziquantel 1
Ilunocitinib 1

Hyposalivation Reaction Insights

10 reports name Hyposalivation; 2 recorded a death outcome (20.0% of reported events, not a population-level mortality rate). VeDDRA code: 1076.

By species: Dog (7 reports), Human (1 reports), Cat (1 reports). By breed: Boxer (German Boxer) (1), Terrier - Jack Russell (1), Unknown (1).

Most co-reported drugs: Carprofen (1 reports), Firocoxib (1 reports), Ethoxydiglycol + Phytosphingosine 1% + Polyvinylpyrrolidone (1 reports), Febantel + Praziquantel + Pyrantel Pamoate (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.