Reaction profile

The FDA adverse-event record for hyposalivation

10 FDA reports name hyposalivation, a lower-volume reaction in the CVM extract (VeDDRA 1076). Plate stamps and neighbourhood peers follow.

#2457 of 2,481
by report volume (all reactions)
10
reports citing this reaction
20.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hyposalivation has 10 reports now versus 10 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hyposalivation changes

FDA AER · VeDDRA plate

Code 1076 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 10 reports
  • DEATH-HOT 20.0%
  • BOTTOM-DECILE #2457/2481
  • PHOTO-FINISH Anoxia
  • SPECIES-DOG Dog · 7
  • DRUG-LEAD Carprofen · 1
  • DESK-WIDE 10 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Anoxia (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Hyposalivation

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Anoxia · near10Blackout · near10BLOOD CHEMISTRY ABNOR… · near10Bronchial secretion · near10Hyposalivation · this reacti…10Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hyposalivation

What the FDA AER plate says about Hyposalivation

Signature read: 10 reports place Hyposalivation in the lower third of FDA AER volume (#2457 of 2,481). Report volume is lower-third scale: 10 named reports in the openFDA extract. 2 of 10 reports were death-coded (20.0% of named reports, not a population mortality rate). Nearest volume peer: Anoxia (±0 reports). Lead species Dog (7). Lead co-reported drug Carprofen (1).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 7
Human 1
Cat 1
Horse 1

Breeds Most Affected

Boxer (German Boxer) 1
Terrier - Jack Russell 1
Unknown 1
Poodle - Miniature 1
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) 1
Domestic Shorthair 1
Thoroughbred 1
Borzoi 1
Chihuahua 1
Pit Bull 1

Associated Drugs

Carprofen 1
Firocoxib 1
Ethoxydiglycol + Phytosphingosine 1% + Polyvinylpyrrolidone 1
Febantel + Praziquantel + Pyrantel Pamoate 1
Dexmedetomidine Hydrochloride 1
Atipamezole Hydrochloride 1
Butorphanol Tartrate 1
Dexamethasone + Neomycin Sulfate + Thiabendazole 1
Ivermectin + Praziquantel 1
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 1
Alfaxalone 1
Salicylic Acid 1
Milbemycin Oxime 1
Milbemycin Oxime + Praziquantel 1
Ilunocitinib 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hyposalivation (#2457 of 2,481 by report volume); death-coded 20.0%. PlainBreed reaction plate · report volume stamp 10 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →