Reaction profile

The FDA adverse-event record for scleritis

116 FDA adverse-event reports reference scleritis (VeDDRA 473). See the species, breeds, and drugs most associated with it below.

116
reports citing this reaction
13.8%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
116
Total Reports
16
Deaths
13.8%
Death Rate

Species Most Affected

Dog 105
Cat 8
Cattle 2
Horse 1

Breeds Most Affected

Crossbred Canine/dog 9
Retriever - Labrador 9
Shih Tzu 9
Chihuahua 6
Dachshund (unspecified) 6
Terrier - Boston 4
Pit Bull 4
Terrier (unspecified) 4
Boxer (German Boxer) 4
Pug 4

Associated Drugs

Milbemycin Oxime + Spinosad 14
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 13
Spinosad 10
Carprofen 8
Moxidectin 7
Oclacitinib Maleate 6
Imidacloprid + Moxidectin 6
Prednisone 5
Recombinant Human Insulin 5
Diphenhydramine 5
Cefovecin Sodium 4
Deracoxib 4
Enrofloxacin 4
Maropitant Citrate 4
Cyclosporine 3
Meloxicam 3
Tresaderm Dermatological Solution 3
Trilostane 3
Hyaluronic Acid 3
Rabies Vaccine 3

Scleritis Reaction Insights

116 reports name Scleritis; 16 recorded a death outcome (13.8% of reported events, not a population-level mortality rate). VeDDRA code: 473.

By species: Dog (105 reports), Cat (8 reports), Cattle (2 reports). By breed: Crossbred Canine/dog (9), Retriever - Labrador (9), Shih Tzu (9).

Most co-reported drugs: Milbemycin Oxime + Spinosad (14 reports), Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (13 reports), Spinosad (10 reports), Carprofen (8 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.