Reaction profile

The FDA adverse-event record for pyuria

590 FDA adverse-event reports reference pyuria (VeDDRA 2255). See the species, breeds, and drugs most associated with it below.

590
reports citing this reaction
16.1%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
590
Total Reports
95
Deaths
16.1%
Death Rate

Species Most Affected

Dog 505
Cat 82
Horse 3

Breeds Most Affected

Retriever - Labrador 71
Domestic Shorthair 53
Crossbred Canine/dog 40
Shepherd Dog - German 21
Shih Tzu 19
Boxer (German Boxer) 19
Retriever - Golden 19
Beagle 18
Chihuahua 14
Collie - Border 12

Associated Drugs

Trilostane 140
Bedinvetmab 117
Carprofen 65
Gabapentin 55
Oclacitinib Maleate 42
Fluralaner Chew Tablets 38
Maropitant Citrate 34
Afoxolaner 26
Moxidectin 24
Meloxicam 22
Prednisone 16
Cefovecin 16
Fluralaner 13.64% 12-Week Chew 16
Milbemycin Oxime + Spinosad 15
Grapiprant 15
Ivermectin + Pyrantel As Pamoate Salt 12
Enrofloxacin 12
Metronidazole 12
Pimobendan 12
Velagliflozin Proline Monohydrate 12

Pyuria Reaction Insights

590 reports name Pyuria; 95 recorded a death outcome (16.1% of reported events, not a population-level mortality rate). VeDDRA code: 2255.

By species: Dog (505 reports), Cat (82 reports), Horse (3 reports). By breed: Retriever - Labrador (71), Domestic Shorthair (53), Crossbred Canine/dog (40).

Most co-reported drugs: Trilostane (140 reports), Bedinvetmab (117 reports), Carprofen (65 reports), Gabapentin (55 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.