Reaction profile

The FDA adverse-event record for easily startled

41 FDA adverse-event reports reference easily startled (VeDDRA 3061). See the species, breeds, and drugs most associated with it below.

41
reports citing this reaction
4.9%
death-coded share
Dog
most-affected species
Fluralaner 13.64% 12-Week Chew
most-associated drug
Verify with FDA CVM →
41
Total Reports
2
Deaths
4.9%
Death Rate

Species Most Affected

Dog 30
Cat 11

Breeds Most Affected

Domestic Shorthair 7
Terrier (unspecified) 4
Retriever - Labrador 3
Terrier - West Highland White 2
Crossbred Canine/dog 2
Retriever - Golden 2
Terrier - Yorkshire 2
Great Pyrenees 2
Cat (other) 2
Corgi (unspecified) 1

Associated Drugs

Fluralaner 13.64% 12-Week Chew 7
Pyrantel Pamoate;Sarolaner 6
Sarolaner 3
Buprenorphine 3
Milbemycin Oxime 2
Bedinvetmab 2
Dexmedetomidine 2
Ketamine 2
Selamectin;Sarolaner 2
Anti-Nausea Injection 1
Prednisone 1
Anticonvulsant 1
Fluid Therapy (Unknown) 1
Amoxicillin 1
Fluralaner Spot-On Solution 1
Butorphanol Tartrate 1
0.15% Ketoconazole, 0.15% Chlorhexidine In Usp Trizedta 1
Propofol 1
Isoflurane 1
Genta/Betamet/Clotrim Ear Oint 1

Easily startled Reaction Insights

41 reports name Easily startled; 2 recorded a death outcome (4.9% of reported events, not a population-level mortality rate). VeDDRA code: 3061.

By species: Dog (30 reports), Cat (11 reports). By breed: Domestic Shorthair (7), Terrier (unspecified) (4), Retriever - Labrador (3).

Most co-reported drugs: Fluralaner 13.64% 12-Week Chew (7 reports), Pyrantel Pamoate;Sarolaner (6 reports), Sarolaner (3 reports), Buprenorphine (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.