Hepatic disorder NOS
VeDDRA Code: 1520
322 adverse event reports referencing this reaction
322
Total Reports
158
Deaths
4910.0%
Death Rate
Species Most Affected
Dog 254
Cat 50
Cattle 8
Horse 5
Pig 2
Sheep 1
Other Rodents 1
Chicken 1
Breeds Most Affected
Retriever - Labrador 39
Domestic Shorthair 33
Crossbred Canine/dog 19
Shih Tzu 12
Dog (unknown) 12
Shepherd Dog - German 9
Rottweiler 9
Siberian Husky 7
Terrier - Yorkshire 7
Domestic Longhair 7
Associated Drugs
Milbemycin Oxime + Spinosad 55
Carprofen 46
Trilostane 26
Spinosad 25
Fluralaner Chew Tablets 23
Maropitant Citrate 16
Gabapentin 14
Oclacitinib Maleate 13
Bedinvetmab 12
Rabies Vaccine 11
Famotidine 11
Fluralaner 13.64% 12-Week Chew 11
Buprenorphine 9
Monensin Sodium 8
Sam-E, Silybin, Vitamin E, Zinc 8
Prednisone 8
Afoxolaner 8
Ivermectin + Pyrantel As Pamoate Salt 8
Grapiprant 8
Enrofloxacin 7
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.