Reaction profile

The FDA adverse-event record for aplastic anaemia

27 FDA reports name aplastic anaemia, a lower-volume reaction in the CVM extract (VeDDRA 146). Plate stamps and neighbourhood peers follow.

#2036 of 2,481
by report volume (all reactions)
27
reports citing this reaction
55.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Aplastic anaemia has 27 reports now versus 27 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Aplastic anaemia changes

FDA AER · VeDDRA plate

Code 146 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 27 reports
  • DEATH-HOT 55.6%
  • LOWER-Q #2036/2481
  • PHOTO-FINISH Abortion spontaneous
  • SPECIES-DOG Dog · 18
  • DRUG-LEAD Cefovecin Sodium · 5
  • DESK-WIDE 19 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abortion spontaneous (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Aplastic anaemia

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abortion spontaneous · near27Aplastic anaemia · this reac…27Cyanotic spots/blotch… · near27Cyst rupture NOS · near27Decubitus · near27Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Aplastic anaemia

Aplastic anaemia: high death-coded share in the FDA AER plate

Signature read: Aplastic anaemia's 55.6% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 27 named reports in the openFDA extract. Death-coded share is upper-third: 15 of 27 reports (55.6% of named reports). Nearest volume peer: Abortion spontaneous (±0 reports). Lead species Dog (18). Lead co-reported drug Cefovecin Sodium (5).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 18
Cat 9

Breeds Most Affected

Domestic (unspecified) 3
Domestic Shorthair 3
Beagle 2
Rottweiler 2
Domestic Mediumhair 2
Retriever - Labrador 2
Terrier - Rat 1
Crossbred Canine/dog 1
Shepherd Dog - Australian 1
Terrier - Yorkshire 1

Associated Drugs

Cefovecin Sodium 5
Doxycycline 5
Carprofen 4
Prednisone 4
Cefovecin 2
Cyclosporine 2
Melarsomine Dihydrochloride 2
Fluralaner Spot-On Solution 2
Estriol Tablets 2
Leflunomide 1
Marbofloxacin 1
Plasma 1
Spinosad 1
Milbemycin Oxime + Lufenuron 1
Melarsomine Dihydrochloride Injection 1
Moxidectin 1
Diazepam 1
Phenobarbital 1
Cefpodoxime Proxetil 1
Leptospira Canicola L-15 Strain C-51; Leptospira Grippotyphosa 1550 Lot 10005 St 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Aplastic anaemia (#2036 of 2,481 by report volume); death-coded 55.6%. PlainBreed reaction plate · death-coded share stamp 55.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →