Reaction profile

The FDA adverse-event record for aplastic anaemia

26 FDA adverse-event reports reference aplastic anaemia (VeDDRA 146). See the species, breeds, and drugs most associated with it below.

26
reports citing this reaction
57.7%
death-coded share
Dog
most-affected species
Cefovecin Sodium
most-associated drug
Verify with FDA CVM →
26
Total Reports
15
Deaths
57.7%
Death Rate

Species Most Affected

Dog 17
Cat 9

Breeds Most Affected

Domestic (unspecified) 3
Domestic Shorthair 3
Rottweiler 2
Domestic Mediumhair 2
Retriever - Labrador 2
Terrier - Rat 1
Beagle 1
Crossbred Canine/dog 1
Shepherd Dog - Australian 1
Boxer (German Boxer) 1

Associated Drugs

Cefovecin Sodium 5
Carprofen 4
Doxycycline 4
Prednisone 3
Cefovecin 2
Cyclosporine 2
Melarsomine Dihydrochloride 2
Fluralaner Spot-On Solution 2
Estriol Tablets 2
Leflunomide 1
Marbofloxacin 1
Plasma 1
Melarsomine Dihydrochloride Injection 1
Spinosad 1
Milbemycin Oxime + Lufenuron 1
Moxidectin 1
Diazepam 1
Phenobarbital 1
Cefpodoxime Proxetil 1
Leptospira Canicola L-15 Strain C-51; Leptospira Grippotyphosa 1550 Lot 10005 St 1

Aplastic anaemia Reaction Insights

26 reports name Aplastic anaemia; 15 recorded a death outcome (57.7% of reported events, not a population-level mortality rate). VeDDRA code: 146.

By species: Dog (17 reports), Cat (9 reports). By breed: Domestic (unspecified) (3), Domestic Shorthair (3), Rottweiler (2).

Most co-reported drugs: Cefovecin Sodium (5 reports), Carprofen (4 reports), Doxycycline (4 reports), Prednisone (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.