Reaction profile

The FDA adverse-event record for pulmonary hypertension

77 FDA adverse-event reports reference pulmonary hypertension (VeDDRA 2559). See the species, breeds, and drugs most associated with it below.

77
reports citing this reaction
22.1%
death-coded share
Dog
most-affected species
Pimobendan
most-associated drug
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77
Total Reports
17
Deaths
22.1%
Death Rate

Species Most Affected

Dog 72
Cat 5

Breeds Most Affected

Crossbred Canine/dog 16
Chihuahua 7
Terrier - Boston 4
Spaniel - King Charles Cavalier 3
Dachshund (unspecified) 3
Shih Tzu 3
Maltese 3
Terrier - Yorkshire 2
Spitz - German Pomeranian 2
Domestic Longhair 2

Associated Drugs

Pimobendan 14
Trilostane 9
Prednisone 8
Doxycycline 7
Ivermectin + Pyrantel As Pamoate Salt 6
Melarsomine Dihydrochloride 6
Fluralaner 13.64% 12-Week Chew 6
Vetmedin Pimobendan Chewable 2.5 Mg Np 6
Bedinvetmab 6
Milbemycin Oxime + Praziquantel 4
Moxidectin 4
Pyrantel Pamoate;Sarolaner 4
Sildenafil 4
Grapiprant 3
Carprofen 3
Hydrocodone 3
Sarolaner 3
Melarsomine 3
Maropitant Citrate 3
Gabapentin 3

Pulmonary hypertension Reaction Insights

77 reports name Pulmonary hypertension; 17 recorded a death outcome (22.1% of reported events, not a population-level mortality rate). VeDDRA code: 2559.

By species: Dog (72 reports), Cat (5 reports). By breed: Crossbred Canine/dog (16), Chihuahua (7), Terrier - Boston (4).

Most co-reported drugs: Pimobendan (14 reports), Trilostane (9 reports), Prednisone (8 reports), Doxycycline (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.