Reaction profile

The FDA adverse-event record for pulmonary hypertension

84 FDA adverse-event reports reference pulmonary hypertension (VeDDRA 2559). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1480 of 2,481
by report volume (all reactions)
84
reports citing this reaction
21.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pulmonary hypertension has 84 reports now versus 81 in that prior snapshot: 3 more (3.7%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.8 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pulmonary hypertension changes

FDA AER · VeDDRA plate

Code 2559 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 84 reports
  • DEATH-HOT 21.4%
  • MID-PACK #1480/2481
  • PHOTO-FINISH Lichenification
  • SPECIES-DOG Dog · 79
  • DRUG-LEAD Pimobendan · 14
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Lichenification (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Pulmonary hypertension

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Dental plaque · near85Lichenification · near84Pulmonary hypertension · thi…84Slow reflexes · near84Destructive behaviour · near83Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pulmonary hypertension

What the FDA AER plate says about Pulmonary hypertension

Signature read: death-coded share at 21.4% is the most distinctive outcome stamp on Pulmonary hypertension. Report volume sits in the middle third of the reaction corpus. 18 of 84 reports were death-coded (21.4% of named reports, not a population mortality rate). Nearest volume peer: Lichenification (±0 reports). Lead species Dog (79). Lead co-reported drug Pimobendan (14).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Pimobendan appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 79
Cat 5

Breeds Most Affected

Crossbred Canine/dog 16
Chihuahua 10
Terrier - Boston 4
Spaniel - King Charles Cavalier 3
Dachshund (unspecified) 3
Shih Tzu 3
Maltese 3
Dog (unknown) 3
Spitz - German Pomeranian 2
Terrier - Yorkshire 2

Associated Drugs

Pimobendan 14
Trilostane 13
Prednisone 9
Doxycycline 7
Bedinvetmab 7
Ivermectin + Pyrantel As Pamoate Salt 6
Melarsomine Dihydrochloride 6
Fluralaner 13.64% 12-Week Chew 6
Vetmedin Pimobendan Chewable 2.5 Mg Np 6
Gabapentin 6
Carprofen 5
Moxidectin 5
Maropitant Citrate 5
Milbemycin Oxime + Praziquantel 4
Pyrantel Pamoate;Sarolaner 4
Sildenafil 4
Grapiprant 3
Hydrocodone 3
Sarolaner 3
Melarsomine 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Pulmonary hypertension, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (84 here).

Similar death-coded share

Nearest other reactions by death-coded share (21.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pulmonary hypertension (#1480 of 2,481 by report volume); death-coded 21.4%. PlainBreed reaction plate · death-coded share stamp 21.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →