Reaction profile

The FDA adverse-event record for excessive sweating

86 FDA adverse-event reports reference excessive sweating (VeDDRA 1453). See the species, breeds, and drugs most associated with it below.

86
reports citing this reaction
15.1%
death-coded share
Horse
most-affected species
Ceftiofur Crystalline Free Acid
most-associated drug
Verify with FDA CVM →
86
Total Reports
13
Deaths
15.1%
Death Rate

Species Most Affected

Horse 66
Human 9
Dog 6
Cattle 3
Cat 1
Donkey 1

Breeds Most Affected

Quarter Horse 19
Horse (unknown) 13
Unknown 9
Thoroughbred 8
Arab 5
Warmblood (unspecified) 3
Hanovarian 3
Appaloosa 3
Paint 2
Dog (unknown) 2

Associated Drugs

Ceftiofur Crystalline Free Acid 13
Detomidine Hydrochloride 11
Dinoprost Tromethamine 6
Clenbuterol Hydrochloride 5
Pergolide Mesylate 4
Clodronate Disodium 4
Butorphanol Tartrate 4
Fluralaner Chew Tablets 3
Firocoxib 3
Ractopamine Hydrochloride 2
Detomidine 2
Phenylbutazone 2
Enrofloxacin 2
Dexamethasone 2
Ivermectin + Praziquantel 2
Xylazine 2
Altrenogest Oily Solution 2
Pentosan Polysulfate Sodium 2
Selamectin 1
Milbemycin Oxime + Spinosad 1

Excessive sweating Reaction Insights

86 reports name Excessive sweating; 13 recorded a death outcome (15.1% of reported events, not a population-level mortality rate). VeDDRA code: 1453.

By species: Horse (66 reports), Human (9 reports), Dog (6 reports). By breed: Quarter Horse (19), Horse (unknown) (13), Unknown (9).

Most co-reported drugs: Ceftiofur Crystalline Free Acid (13 reports), Detomidine Hydrochloride (11 reports), Dinoprost Tromethamine (6 reports), Clenbuterol Hydrochloride (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.