Excessive sweating

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VeDDRA Code: 1453

86 adverse event reports referencing this reaction

86
Total Reports
13
Deaths
1510.0%
Death Rate

Species Most Affected

Horse 66
Human 9
Dog 6
Cattle 3
Cat 1
Donkey 1

Breeds Most Affected

Quarter Horse 19
Horse (unknown) 13
Unknown 9
Thoroughbred 8
Arab 5
Warmblood (unspecified) 3
Hanovarian 3
Appaloosa 3
Paint 2
Dog (unknown) 2

Associated Drugs

Ceftiofur Crystalline Free Acid 13
Detomidine Hydrochloride 11
Dinoprost Tromethamine 6
Clenbuterol Hydrochloride 5
Pergolide Mesylate 4
Clodronate Disodium 4
Butorphanol Tartrate 4
Fluralaner Chew Tablets 3
Firocoxib 3
Ractopamine Hydrochloride 2
Detomidine 2
Phenylbutazone 2
Enrofloxacin 2
Dexamethasone 2
Ivermectin + Praziquantel 2
Xylazine 2
Altrenogest Oily Solution 2
Pentosan Polysulfate Sodium 2
Selamectin 1
Milbemycin Oxime + Spinosad 1

Data Summary

Metric Value
Total reports referencing reaction 86
Reports with fatal outcome 13
Case-fatality rate (reported events) 1510.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1453.

Excessive sweating Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 86 adverse event reports that reference Excessive sweating as a reaction term, including 13 reports with a death outcome — a 1510.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1453, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Excessive sweating appears most frequently in reports for Horse (66 reports), Human (9 reports), Dog (6 reports) — with Horse dominating at 66 entries. Within those species, the breeds most often named alongside this reaction are Quarter Horse (19), Horse (unknown) (13), Unknown (9). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Excessive sweating are Ceftiofur Crystalline Free Acid (13 reports), Detomidine Hydrochloride (11 reports), Dinoprost Tromethamine (6 reports), Clenbuterol Hydrochloride (5 reports), with Ceftiofur Crystalline Free Acid appearing alongside this reaction in 13 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial