Reaction profile

The FDA adverse-event record for alopecia general

369 FDA adverse-event reports reference alopecia general (VeDDRA 898). See the species, breeds, and drugs most associated with it below.

369
reports citing this reaction
4.6%
death-coded share
Dog
most-affected species
Imidacloprid + Moxidectin
most-associated drug
Verify with FDA CVM →
369
Total Reports
17
Deaths
4.6%
Death Rate

Species Most Affected

Dog 225
Cat 121
Cattle 11
Horse 6
Sheep 3
Unknown 1
Ferret 1
Donkey 1

Breeds Most Affected

Domestic Shorthair 70
Retriever - Labrador 24
Chihuahua 15
Crossbred Canine/dog 14
Domestic Mediumhair 13
Shepherd Dog - German 11
Pit Bull 10
Terrier - Yorkshire 8
Domestic Longhair 7
Shih Tzu 6

Associated Drugs

Imidacloprid + Moxidectin 71
Selamectin 34
Emodepside + Praziquantel 25
Trilostane 25
Milbemycin Oxime + Spinosad 23
Fluralaner Chew Tablets 18
Spinosad 14
Fluralaner Spot-On Solution 14
Oclacitinib Maleate 12
Prednisone 11
Moxidectin 10
Cefovecin 10
Nitenpyram 10
Afoxolaner 10
Melarsomine Dihydrochloride 9
Enrofloxacin 8
Cephalexin 7
Imidacloprid 7
Flumethrin-Imidacloprid 7
Dexamethasone 6

Alopecia general Reaction Insights

369 reports name Alopecia general; 17 recorded a death outcome (4.6% of reported events, not a population-level mortality rate). VeDDRA code: 898.

By species: Dog (225 reports), Cat (121 reports), Cattle (11 reports). By breed: Domestic Shorthair (70), Retriever - Labrador (24), Chihuahua (15).

Most co-reported drugs: Imidacloprid + Moxidectin (71 reports), Selamectin (34 reports), Emodepside + Praziquantel (25 reports), Trilostane (25 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.